Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569236388> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1569236388 endingPage "7" @default.
- W1569236388 startingPage "1" @default.
- W1569236388 abstract "Resistance to amikacin, gentamicin, and tobramycin was surveyed prospectively during controlled aminoglycoside usage in 14 hospitals. Following an initial baseline period (minimum, three months) during which gentamicin use predominated, gentamicin and tobramycin were placed on restrictive control, establishing amikacin as the aminoglycoside of general use (86 percent of total aminoglycoside usage). During an average of 35 months' restriction of gentamicin and tobramycin, significant reductions in gram-negative resistance to gentamicin (8.4 to 7.0 percent, p less than 0.001) and tobramycin (6.0 to 5.3 percent, p less than 0.01) were observed. The most significant decreases in resistance to gentamicin and tobramycin (p less than 0.001) were found for Pseudomonas aeruginosa, Klebsiella species, Serratia species, and Proteus species. Amikacin resistance among gram-negative bacilli was observed to increase marginally from 1.4 to 1.7 percent (p less than 0.05) during the surveillance period, primarily due to a significant increase in resistance among P. aeruginosa (3.0 to 3.9 percent, p = 0.05). These data were compared with data from a similar surveillance program at the 700-bed Minneapolis Veterans Administration Medical Center. Over a period of 54 months, both gentamicin and tobramycin resistance decreased significantly when amikacin was used (p less than 0.001), then increased with reintroduction of gentamicin (p less than 0.05), and decreased significantly with reintroduction of amikacin (p less than 0.001). Despite predominant amikacin use for a total of 38 months, amikacin resistance did not increase and actually decreased significantly (p less than 0.05) in the last 12 months." @default.
- W1569236388 created "2016-06-24" @default.
- W1569236388 creator A5001818619 @default.
- W1569236388 creator A5002008542 @default.
- W1569236388 date "1985-07-01" @default.
- W1569236388 modified "2023-10-06" @default.
- W1569236388 title "Aminoglycoside resistance in gram-negative bacilli during increased amikacin use" @default.
- W1569236388 cites W1976497195 @default.
- W1569236388 cites W1982361720 @default.
- W1569236388 cites W1998143198 @default.
- W1569236388 cites W1998820303 @default.
- W1569236388 cites W2005736219 @default.
- W1569236388 cites W2008810043 @default.
- W1569236388 cites W2023752063 @default.
- W1569236388 cites W2066628129 @default.
- W1569236388 cites W2068114555 @default.
- W1569236388 cites W2071617797 @default.
- W1569236388 cites W2076899615 @default.
- W1569236388 cites W2094203063 @default.
- W1569236388 cites W2106058437 @default.
- W1569236388 cites W2122720908 @default.
- W1569236388 cites W2129945582 @default.
- W1569236388 cites W2143960308 @default.
- W1569236388 cites W2317347377 @default.
- W1569236388 doi "https://doi.org/10.1016/0002-9343(85)90184-6" @default.
- W1569236388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4025364" @default.
- W1569236388 hasPublicationYear "1985" @default.
- W1569236388 type Work @default.
- W1569236388 sameAs 1569236388 @default.
- W1569236388 citedByCount "82" @default.
- W1569236388 countsByYear W15692363882013 @default.
- W1569236388 countsByYear W15692363882014 @default.
- W1569236388 countsByYear W15692363882015 @default.
- W1569236388 countsByYear W15692363882017 @default.
- W1569236388 countsByYear W15692363882018 @default.
- W1569236388 countsByYear W15692363882019 @default.
- W1569236388 countsByYear W15692363882021 @default.
- W1569236388 crossrefType "journal-article" @default.
- W1569236388 hasAuthorship W1569236388A5001818619 @default.
- W1569236388 hasAuthorship W1569236388A5002008542 @default.
- W1569236388 hasConcept C126322002 @default.
- W1569236388 hasConcept C2775832221 @default.
- W1569236388 hasConcept C2777427914 @default.
- W1569236388 hasConcept C2777637488 @default.
- W1569236388 hasConcept C2777787772 @default.
- W1569236388 hasConcept C2778974779 @default.
- W1569236388 hasConcept C501593827 @default.
- W1569236388 hasConcept C523546767 @default.
- W1569236388 hasConcept C54355233 @default.
- W1569236388 hasConcept C71924100 @default.
- W1569236388 hasConcept C86803240 @default.
- W1569236388 hasConcept C89423630 @default.
- W1569236388 hasConceptScore W1569236388C126322002 @default.
- W1569236388 hasConceptScore W1569236388C2775832221 @default.
- W1569236388 hasConceptScore W1569236388C2777427914 @default.
- W1569236388 hasConceptScore W1569236388C2777637488 @default.
- W1569236388 hasConceptScore W1569236388C2777787772 @default.
- W1569236388 hasConceptScore W1569236388C2778974779 @default.
- W1569236388 hasConceptScore W1569236388C501593827 @default.
- W1569236388 hasConceptScore W1569236388C523546767 @default.
- W1569236388 hasConceptScore W1569236388C54355233 @default.
- W1569236388 hasConceptScore W1569236388C71924100 @default.
- W1569236388 hasConceptScore W1569236388C86803240 @default.
- W1569236388 hasConceptScore W1569236388C89423630 @default.
- W1569236388 hasIssue "1" @default.
- W1569236388 hasLocation W15692363881 @default.
- W1569236388 hasLocation W15692363882 @default.
- W1569236388 hasOpenAccess W1569236388 @default.
- W1569236388 hasPrimaryLocation W15692363881 @default.
- W1569236388 hasRelatedWork W2112277666 @default.
- W1569236388 hasRelatedWork W2115593551 @default.
- W1569236388 hasRelatedWork W2119381352 @default.
- W1569236388 hasRelatedWork W224714992 @default.
- W1569236388 hasRelatedWork W2278858577 @default.
- W1569236388 hasRelatedWork W2358470352 @default.
- W1569236388 hasRelatedWork W2414357953 @default.
- W1569236388 hasRelatedWork W2888618318 @default.
- W1569236388 hasRelatedWork W3177131697 @default.
- W1569236388 hasRelatedWork W3186528186 @default.
- W1569236388 hasVolume "79" @default.
- W1569236388 isParatext "false" @default.
- W1569236388 isRetracted "false" @default.
- W1569236388 magId "1569236388" @default.
- W1569236388 workType "article" @default.