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- W1569247537 abstract "There is a high incidence of autoimmune disease in patients with primary immunodeficiency. In almost all instances autoantibodies are to antigenic determinants of the formed elements of the blood — erythrocytes, platelets and neutrophils. In some rare cases, autoantibodies to T or B lymphocytes can cause immunodeficiency. IgA is unique in inciting autoantibodies to this serum protein in some patients with IgA deficiency. Organ-specific autoimmune disease is extremely rare in immunodeficiency states. In contrast, drug allergy and allergic contact dermatitis are extremely common in patients with deficiencies of B lymphocytes. Patients with the syndrome of immunodeficiency with elevated IgM (hyper-IgM deficiency) almost invariably develop autoantibodies to formed elements of the blood. Autoantibody production can be suppressed with anti-idiotypic antibodies." @default.
- W1569247537 created "2016-06-24" @default.
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- W1569247537 date "2007-09-28" @default.
- W1569247537 modified "2023-09-23" @default.
- W1569247537 title "Autoimmunity and Immunodeficiency Disease" @default.
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- W1569247537 doi "https://doi.org/10.1002/9780470513484.ch10" @default.
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