FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569294232> ?p ?o ?g. }

• W1569294232 abstract "Background Acetaminophen is frequently prescribed for treating patients with the common cold, but there is little evidence as to whether it is effective. Objectives To determine the efficacy and safety of acetaminophen in the treatment of the common cold in adults. Search methods We searched CENTRAL 2013, Issue 1, Ovid MEDLINE (1950 to January week 5, 2013), EMBASE (1980 to February 2013), CINAHL (1982 to February 2013) and LILACS (1985 to February 2013). Selection criteria We included randomised controlled trials (RCTs) comparing acetaminophen to placebo or no treatment in adults with the common cold. Studies were included if the trials used acetaminophen as one ingredient of a combination therapy. We excluded studies in which the participants had complications. Primary outcomes included subjective symptom score and duration of common cold symptoms. Secondary outcomes were overall well being, adverse events and financial costs. Data collection and analysis Two review authors independently screened studies for inclusion, assessed risk of bias and extracted data. We performed standard statistical analyses. Main results We included four RCTs involving 758 participants. We did not pool data because of heterogeneity in study designs, outcomes and time points. The studies provided sparse information about effects longer than a few hours, as three of four included studies were short trials of only four to six hours. Participants treated with acetaminophen had significant improvements in nasal obstruction in two of the four studies. One study showed that acetaminophen was superior to placebo in decreasing rhinorrhoea severity, but was not superior for treating sneezing and coughing. Acetaminophen did not improve sore throat or malaise in two of the four studies. Results were inconsistent for some symptoms. Two studies showed that headache and achiness improved more in the acetaminophen group than in the placebo group, while one study showed no difference between the acetaminophen and placebo group. None of the included studies reported the duration of common cold symptoms. Minor side effects (including gastrointestinal adverse events, dizziness, dry mouth, somnolence and increased sweating) in the acetaminophen group were reported in two of the four studies. One of them used a combination of pseudoephedrine and acetaminophen. Authors' conclusions Acetaminophen may help relieve nasal obstruction and rhinorrhoea but does not appear to improve some other cold symptoms (including sore throat, malaise, sneezing and cough). However, two of the four included studies in this review were small and allocation concealment was unclear in all four studies. The data in this review do not provide sufficient evidence to inform practice regarding the use of acetaminophen for the common cold in adults. Further large‐scale, well‐designed trials are needed to determine whether this intervention is beneficial in the treatment of adults with the common cold." @default.
• W1569294232 created "2016-06-24" @default.
• W1569294232 creator A5002698291 @default.
• W1569294232 creator A5005584314 @default.
• W1569294232 creator A5009705311 @default.
• W1569294232 creator A5023307603 @default.
• W1569294232 creator A5028216952 @default.
• W1569294232 creator A5055640195 @default.
• W1569294232 date "2013-07-01" @default.
• W1569294232 modified "2023-10-05" @default.
• W1569294232 title "Acetaminophen (paracetamol) for the common cold in adults" @default.
• W1569294232 cites W1673033778 @default.
• W1569294232 cites W1864675351 @default.
• W1569294232 cites W1894861172 @default.
• W1569294232 cites W1906124091 @default.
• W1569294232 cites W1973073198 @default.
• W1569294232 cites W1974011879 @default.
• W1569294232 cites W1981001019 @default.
• W1569294232 cites W1990035536 @default.
• W1569294232 cites W1991436630 @default.
• W1569294232 cites W1991562066 @default.
• W1569294232 cites W1998799377 @default.
• W1569294232 cites W2001565970 @default.
• W1569294232 cites W2025295475 @default.
• W1569294232 cites W2027510476 @default.
• W1569294232 cites W2029126943 @default.
• W1569294232 cites W2070442907 @default.
• W1569294232 cites W2090388047 @default.
• W1569294232 cites W2091614628 @default.
• W1569294232 cites W2093359923 @default.
• W1569294232 cites W2107533173 @default.
• W1569294232 cites W2108345886 @default.
• W1569294232 cites W2112492031 @default.
• W1569294232 cites W2115115096 @default.
• W1569294232 cites W2123039694 @default.
• W1569294232 cites W2125435699 @default.
• W1569294232 cites W2129309450 @default.
• W1569294232 cites W2153771979 @default.
• W1569294232 cites W2163487689 @default.
• W1569294232 cites W2164679979 @default.
• W1569294232 cites W2172050318 @default.
• W1569294232 cites W39094856 @default.
• W1569294232 cites W4211225146 @default.
• W1569294232 cites W4232798530 @default.
• W1569294232 cites W4233400666 @default.
• W1569294232 cites W4247048705 @default.
• W1569294232 cites W4247822890 @default.
• W1569294232 cites W4256376532 @default.
• W1569294232 doi "https://doi.org/10.1002/14651858.cd008800.pub2" @default.
• W1569294232 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7389565" @default.
• W1569294232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23818046" @default.
• W1569294232 hasPublicationYear "2013" @default.
• W1569294232 type Work @default.
• W1569294232 sameAs 1569294232 @default.
• W1569294232 citedByCount "26" @default.
• W1569294232 countsByYear W15692942322013 @default.
• W1569294232 countsByYear W15692942322014 @default.
• W1569294232 countsByYear W15692942322015 @default.
• W1569294232 countsByYear W15692942322016 @default.
• W1569294232 countsByYear W15692942322017 @default.
• W1569294232 countsByYear W15692942322018 @default.
• W1569294232 countsByYear W15692942322020 @default.
• W1569294232 countsByYear W15692942322021 @default.
• W1569294232 countsByYear W15692942322022 @default.
• W1569294232 countsByYear W15692942322023 @default.
• W1569294232 crossrefType "journal-article" @default.
• W1569294232 hasAuthorship W1569294232A5002698291 @default.
• W1569294232 hasAuthorship W1569294232A5005584314 @default.
• W1569294232 hasAuthorship W1569294232A5009705311 @default.
• W1569294232 hasAuthorship W1569294232A5023307603 @default.
• W1569294232 hasAuthorship W1569294232A5028216952 @default.
• W1569294232 hasAuthorship W1569294232A5055640195 @default.
• W1569294232 hasBestOaLocation W15692942322 @default.
• W1569294232 hasConcept C118552586 @default.
• W1569294232 hasConcept C126322002 @default.
• W1569294232 hasConcept C142724271 @default.
• W1569294232 hasConcept C17744445 @default.
• W1569294232 hasConcept C197934379 @default.
• W1569294232 hasConcept C199539241 @default.
• W1569294232 hasConcept C203014093 @default.
• W1569294232 hasConcept C204787440 @default.
• W1569294232 hasConcept C27081682 @default.
• W1569294232 hasConcept C27415008 @default.
• W1569294232 hasConcept C2778136109 @default.
• W1569294232 hasConcept C2778722691 @default.
• W1569294232 hasConcept C2779473830 @default.
• W1569294232 hasConcept C2781145037 @default.
• W1569294232 hasConcept C42219234 @default.
• W1569294232 hasConcept C71924100 @default.
• W1569294232 hasConceptScore W1569294232C118552586 @default.
• W1569294232 hasConceptScore W1569294232C126322002 @default.
• W1569294232 hasConceptScore W1569294232C142724271 @default.
• W1569294232 hasConceptScore W1569294232C17744445 @default.
• W1569294232 hasConceptScore W1569294232C197934379 @default.
• W1569294232 hasConceptScore W1569294232C199539241 @default.
• W1569294232 hasConceptScore W1569294232C203014093 @default.
• W1569294232 hasConceptScore W1569294232C204787440 @default.
• W1569294232 hasConceptScore W1569294232C27081682 @default.
• W1569294232 hasConceptScore W1569294232C27415008 @default.
• W1569294232 hasConceptScore W1569294232C2778136109 @default.

• next