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- W1569401608 abstract "Zincovit tablets have been used as nutritional food supplement over a prolonged period of time. In previous studies, we had reported combined formulation of grape seed extract and Zincovit tablets for its strong in-vitro, in-vivo antioxidant, anti-hyperglycemic and anti-cataractogenic potential. Consequently, the aim of the present study was to investigate the cardio-protective effect of single combined formulation of grape seed extract and Zincovit tablets using a Langendorff model of ischemia-reperfusion in Wistar rats. Combined formulation of grape seed extract and Zincovit tablets significantly attenuated ischemia-reperfusion induced cardiac injury in terms of increased coronary flow rate, decreased creatine kinase activity in coronary effluent, decreased MDA, 4-HNE and increased protein thiol content in heart tissue homogenate. The present study revealed that the combined formulation of grape seed extract and Zincovit tablet is the potential functional nutritional food supplements that could offer a novel therapeutic opportunity against myocardial ischemia-reperfusion injury in Wistar rats." @default.
- W1569401608 created "2016-06-24" @default.
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- W1569401608 date "2014-09-11" @default.
- W1569401608 modified "2023-09-23" @default.
- W1569401608 title "Grape seed extract and zinc containing multivitaminmineral nutritional food supplement protects heart against myocardial Ischemia-reperfusion injury in wistar rats" @default.
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