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• W1569418278 startingPage "931" @default.
• W1569418278 abstract "Publisher Summary Living organisms are made up of one or more cells, each enclosed by a lipid membrane. Spanning this membrane are specialized protein molecules, called ion channels, which facilitate many cellular processes by selectively controlling the transmembrane movement of small electrically charged ions. Understanding the behaviour of these channels is fundamental to the study of normal and abnormal cell function and regulation. There are many different types of channel, varying in chemical structure, size, location, and function. Ion conduction occurs most commonly through a single aqueous pore with a gate controlled by particular stimuli. Typically, gating appears instantaneous at the usual time scale of observation, so that in the simplest case the gate is effectively closed or fully open. Some well-known channels, such as calcium, chloride, potassium or sodium channels, are classified according to the dominant ion transferred, while others, such as acetylcholine, glycine or glutamate channels, are identified by the neurotransmitter that leads to their activation. Mechanosensitive channels are a more recently discovered class of channels, which are activated by physical stresses." @default.
• W1569418278 created "2016-06-24" @default.
• W1569418278 creator A5023957553 @default.
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• W1569418278 date "2003-01-01" @default.
• W1569418278 modified "2023-10-18" @default.
• W1569418278 title "Ch. 23. Markov modelling of burst behaviour in ion channels" @default.
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• W1569418278 doi "https://doi.org/10.1016/s0169-7161(03)21025-7" @default.
• W1569418278 hasPublicationYear "2003" @default.
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