Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569572117> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1569572117 endingPage "247" @default.
- W1569572117 startingPage "244" @default.
- W1569572117 abstract "Background and Objective: Candida dubliniensis is an opportunistic pathogen originally isolated from AIDS patients and has ability to invade and cause systemic disease in immunocompromised patients as Candida albicans does. Phenotypic switching phenomenon, one of the essential virulence factor, has been firstly found in Candida albicans . It seems to play a role in the switching of Candida from normal flora to pathogenic form. This study has focused on morphologies of different phenotypes during phenotypic switching in Candida dubliniensis . Method: Total 36 isolates of Candida dubliniensis were tested on an indicator medium containing 1 mM CuSO 4 . Cellular morphologies of variant switched-phenotypes were observed under the microscope (400X) by lactophenol cotton blue staining. Result : It was found that the phenotypic switching system in Candida dubliniensis included white (Wh), light brown (LB), dark brown (DB), wrinkle (Wr), fuzzy light brown (Fz) and brain-like appearance (Br) phenotypes. When cell morphologies in each switched phenotypes were observed under the microscope, it was found that white phenotype showed much hyphae production, while other types showed budding yeast form. Conclusion : This study has suggested that filamentous form is more penetrating capable than budding yeast form, thus white phenotype is possible to be a pathogenic form of Candida dubliniensis . However, for more understanding of the pathogenesis, the virulence in each phenotype other than morphogenesis have been further studied. Key words: Candida dubliniensis , phenotypic switching, morphology" @default.
- W1569572117 created "2016-06-24" @default.
- W1569572117 creator A5027324854 @default.
- W1569572117 creator A5063785183 @default.
- W1569572117 creator A5077694844 @default.
- W1569572117 creator A5078268041 @default.
- W1569572117 creator A5091048513 @default.
- W1569572117 date "2013-01-01" @default.
- W1569572117 modified "2023-09-23" @default.
- W1569572117 title "Microscopic morphologies of different switched-phenotypes in Candida dubliniensis" @default.
- W1569572117 cites W1828773039 @default.
- W1569572117 cites W1997437177 @default.
- W1569572117 cites W2082335793 @default.
- W1569572117 cites W2092968924 @default.
- W1569572117 cites W2097214609 @default.
- W1569572117 cites W2160153791 @default.
- W1569572117 hasPublicationYear "2013" @default.
- W1569572117 type Work @default.
- W1569572117 sameAs 1569572117 @default.
- W1569572117 citedByCount "0" @default.
- W1569572117 crossrefType "journal-article" @default.
- W1569572117 hasAuthorship W1569572117A5027324854 @default.
- W1569572117 hasAuthorship W1569572117A5063785183 @default.
- W1569572117 hasAuthorship W1569572117A5077694844 @default.
- W1569572117 hasAuthorship W1569572117A5078268041 @default.
- W1569572117 hasAuthorship W1569572117A5091048513 @default.
- W1569572117 hasConcept C104317684 @default.
- W1569572117 hasConcept C127716648 @default.
- W1569572117 hasConcept C145081991 @default.
- W1569572117 hasConcept C198410946 @default.
- W1569572117 hasConcept C2776445003 @default.
- W1569572117 hasConcept C2776460866 @default.
- W1569572117 hasConcept C2779222958 @default.
- W1569572117 hasConcept C2780917455 @default.
- W1569572117 hasConcept C2781011225 @default.
- W1569572117 hasConcept C2781090273 @default.
- W1569572117 hasConcept C523546767 @default.
- W1569572117 hasConcept C54355233 @default.
- W1569572117 hasConcept C58123911 @default.
- W1569572117 hasConcept C60987743 @default.
- W1569572117 hasConcept C86803240 @default.
- W1569572117 hasConcept C89423630 @default.
- W1569572117 hasConcept C90080823 @default.
- W1569572117 hasConceptScore W1569572117C104317684 @default.
- W1569572117 hasConceptScore W1569572117C127716648 @default.
- W1569572117 hasConceptScore W1569572117C145081991 @default.
- W1569572117 hasConceptScore W1569572117C198410946 @default.
- W1569572117 hasConceptScore W1569572117C2776445003 @default.
- W1569572117 hasConceptScore W1569572117C2776460866 @default.
- W1569572117 hasConceptScore W1569572117C2779222958 @default.
- W1569572117 hasConceptScore W1569572117C2780917455 @default.
- W1569572117 hasConceptScore W1569572117C2781011225 @default.
- W1569572117 hasConceptScore W1569572117C2781090273 @default.
- W1569572117 hasConceptScore W1569572117C523546767 @default.
- W1569572117 hasConceptScore W1569572117C54355233 @default.
- W1569572117 hasConceptScore W1569572117C58123911 @default.
- W1569572117 hasConceptScore W1569572117C60987743 @default.
- W1569572117 hasConceptScore W1569572117C86803240 @default.
- W1569572117 hasConceptScore W1569572117C89423630 @default.
- W1569572117 hasConceptScore W1569572117C90080823 @default.
- W1569572117 hasIssue "4" @default.
- W1569572117 hasLocation W15695721171 @default.
- W1569572117 hasOpenAccess W1569572117 @default.
- W1569572117 hasPrimaryLocation W15695721171 @default.
- W1569572117 hasRelatedWork W150842035 @default.
- W1569572117 hasRelatedWork W1885847088 @default.
- W1569572117 hasRelatedWork W1911466185 @default.
- W1569572117 hasRelatedWork W2016138883 @default.
- W1569572117 hasRelatedWork W2016644594 @default.
- W1569572117 hasRelatedWork W2019731685 @default.
- W1569572117 hasRelatedWork W2067793163 @default.
- W1569572117 hasRelatedWork W2101787825 @default.
- W1569572117 hasRelatedWork W2128849746 @default.
- W1569572117 hasRelatedWork W2131783407 @default.
- W1569572117 hasRelatedWork W2133725114 @default.
- W1569572117 hasRelatedWork W2137497148 @default.
- W1569572117 hasRelatedWork W2158313582 @default.
- W1569572117 hasRelatedWork W2166509005 @default.
- W1569572117 hasRelatedWork W2171510356 @default.
- W1569572117 hasVolume "28" @default.
- W1569572117 isParatext "false" @default.
- W1569572117 isRetracted "false" @default.
- W1569572117 magId "1569572117" @default.
- W1569572117 workType "article" @default.