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• W1569578087 abstract "Elevated inflammatory levels are linked to poorer cognition, but experimental confirmation is lacking. This report examined associations between cognitive performance and inflammation induced by exercise and vaccination. Thirty-six (exercise N = 18, vaccination N = 18) healthy males completed a paced auditory serial addition test (PASAT), which is a multifaceted measure of cognitive function. The task was completed in placebo and elevated inflammation states. Improvements in PASAT performance were related to inflammation. In the exercise study, IL-6 during the first PASAT negatively correlated with PASAT improvement (p = .022). In the vaccination study, increases in C-reactive protein between PASATs correlated with reduced PASAT improvement (p < .001). Inflammation was linked to reduced improvements in cognitive performance. Further research should identify the specific cognitive functions affects and the underlying mechanisms." @default.
• W1569578087 created "2016-06-24" @default.
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• W1569578087 date "2014-11-04" @default.
• W1569578087 modified "2023-09-26" @default.
• W1569578087 title "Induced mild systemic inflammation is associated with impaired ability to improve cognitive task performance by practice" @default.
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• W1569578087 doi "https://doi.org/10.1111/psyp.12360" @default.
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