Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569582665> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1569582665 endingPage "2257" @default.
- W1569582665 startingPage "2253" @default.
- W1569582665 abstract "Fractionation of a crude extract from Saccharomyces cerevisiae X-2180 on Sepharose 6B in the presence of 0.5% Triton X-100 resolves two enzyme fractions containing alpha-mannosidase activity. Fraction I which is excluded from the gel contains alpha-mannosidase activity toward both p-nitrophenyl-alpha-D-mannopyranoside and Man9GlcNAc oligosaccharide as substrates, whereas Fraction II which is included in the gel contains only oligosaccharide alpha-mannosidase activity. The latter enzyme is very specific and removes a single mannose residue from Man9GlcNAc, whereas the alpha-mannosidase activity of Fraction I removes several mannose residues from Man9GlcNAc oligosaccharide. High resolution 1H NMR analysis of the Man8GlcNAc formed from Man9GlcNAc in the presence of the alpha-mannosidase of Fraction II showed only a single isomer with the following structure: (see formula; see text) This specific enzyme is most probably involved in processing of oligosaccharide during biosynthesis of mannoproteins. The mannose analog of 1-deoxynojirimycin (50-500 microM), dideoxy-1,5-imino-D-mannitol, inhibits the oligosaccharide alpha-mannosidase activities of Fractions I and II to about the same extent, but has no effect on the nonspecific alpha-mannosidase which acts on p-nitrophenyl-alpha-D-mannopyranoside." @default.
- W1569582665 created "2016-06-24" @default.
- W1569582665 creator A5028247544 @default.
- W1569582665 creator A5043308905 @default.
- W1569582665 creator A5051234892 @default.
- W1569582665 creator A5054978794 @default.
- W1569582665 creator A5073626041 @default.
- W1569582665 date "1985-02-01" @default.
- W1569582665 modified "2023-10-16" @default.
- W1569582665 title "Characterization of a specific alpha-mannosidase involved in oligosaccharide processing in Saccharomyces cerevisiae." @default.
- W1569582665 cites W1106257837 @default.
- W1569582665 cites W1515555384 @default.
- W1569582665 cites W1516923509 @default.
- W1569582665 cites W1524696858 @default.
- W1569582665 cites W1539737337 @default.
- W1569582665 cites W1561417224 @default.
- W1569582665 cites W1580158514 @default.
- W1569582665 cites W1611254900 @default.
- W1569582665 cites W1974898808 @default.
- W1569582665 cites W2046491869 @default.
- W1569582665 cites W2409234069 @default.
- W1569582665 doi "https://doi.org/10.1016/s0021-9258(18)89546-1" @default.
- W1569582665 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3882690" @default.
- W1569582665 hasPublicationYear "1985" @default.
- W1569582665 type Work @default.
- W1569582665 sameAs 1569582665 @default.
- W1569582665 citedByCount "94" @default.
- W1569582665 countsByYear W15695826652012 @default.
- W1569582665 countsByYear W15695826652013 @default.
- W1569582665 countsByYear W15695826652014 @default.
- W1569582665 countsByYear W15695826652015 @default.
- W1569582665 countsByYear W15695826652016 @default.
- W1569582665 countsByYear W15695826652020 @default.
- W1569582665 countsByYear W15695826652021 @default.
- W1569582665 crossrefType "journal-article" @default.
- W1569582665 hasAuthorship W1569582665A5028247544 @default.
- W1569582665 hasAuthorship W1569582665A5043308905 @default.
- W1569582665 hasAuthorship W1569582665A5051234892 @default.
- W1569582665 hasAuthorship W1569582665A5054978794 @default.
- W1569582665 hasAuthorship W1569582665A5073626041 @default.
- W1569582665 hasBestOaLocation W15695826651 @default.
- W1569582665 hasConcept C159110408 @default.
- W1569582665 hasConcept C181199279 @default.
- W1569582665 hasConcept C185592680 @default.
- W1569582665 hasConcept C2775887612 @default.
- W1569582665 hasConcept C2775944032 @default.
- W1569582665 hasConcept C2777174400 @default.
- W1569582665 hasConcept C2777576037 @default.
- W1569582665 hasConcept C2777726330 @default.
- W1569582665 hasConcept C2777832050 @default.
- W1569582665 hasConcept C2779222958 @default.
- W1569582665 hasConcept C49453240 @default.
- W1569582665 hasConcept C55493867 @default.
- W1569582665 hasConcept C64943373 @default.
- W1569582665 hasConcept C71924100 @default.
- W1569582665 hasConcept C86803240 @default.
- W1569582665 hasConceptScore W1569582665C159110408 @default.
- W1569582665 hasConceptScore W1569582665C181199279 @default.
- W1569582665 hasConceptScore W1569582665C185592680 @default.
- W1569582665 hasConceptScore W1569582665C2775887612 @default.
- W1569582665 hasConceptScore W1569582665C2775944032 @default.
- W1569582665 hasConceptScore W1569582665C2777174400 @default.
- W1569582665 hasConceptScore W1569582665C2777576037 @default.
- W1569582665 hasConceptScore W1569582665C2777726330 @default.
- W1569582665 hasConceptScore W1569582665C2777832050 @default.
- W1569582665 hasConceptScore W1569582665C2779222958 @default.
- W1569582665 hasConceptScore W1569582665C49453240 @default.
- W1569582665 hasConceptScore W1569582665C55493867 @default.
- W1569582665 hasConceptScore W1569582665C64943373 @default.
- W1569582665 hasConceptScore W1569582665C71924100 @default.
- W1569582665 hasConceptScore W1569582665C86803240 @default.
- W1569582665 hasIssue "4" @default.
- W1569582665 hasLocation W15695826651 @default.
- W1569582665 hasOpenAccess W1569582665 @default.
- W1569582665 hasPrimaryLocation W15695826651 @default.
- W1569582665 hasRelatedWork W1522309084 @default.
- W1569582665 hasRelatedWork W1569582665 @default.
- W1569582665 hasRelatedWork W1791436544 @default.
- W1569582665 hasRelatedWork W2004638783 @default.
- W1569582665 hasRelatedWork W2078731644 @default.
- W1569582665 hasRelatedWork W2088385224 @default.
- W1569582665 hasRelatedWork W2221225583 @default.
- W1569582665 hasRelatedWork W2414016706 @default.
- W1569582665 hasRelatedWork W2416070025 @default.
- W1569582665 hasRelatedWork W4254973996 @default.
- W1569582665 hasVolume "260" @default.
- W1569582665 isParatext "false" @default.
- W1569582665 isRetracted "false" @default.
- W1569582665 magId "1569582665" @default.
- W1569582665 workType "article" @default.