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- W1569637573 abstract "This chapter reviews the diverse applications of hydrophilic interaction chromatography (HILIC) to meet the fundamental analytical requirements involved in drug discovery. It describes the current impact and future potential of HILIC for pharmaceutical drug discovery. The subjects considered in this report include both in vitro biological applications and applications supporting discovery chemistry with an emphasis on the stages of lead identification, lead optimization, and candidate selection (CS). Practical considerations from the author's own laboratory on the key chromatographic parameters to be successful on the implementation and application of HILIC for various discovery purposes are briefly discussed." @default.
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- W1569637573 date "2013-03-20" @default.
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- W1569637573 title "Hydrophilic Interaction Chromatography (HILIC) for Drug Discovery" @default.
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- W1569637573 doi "https://doi.org/10.1002/9781118495247.ch5" @default.
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