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- W1569673705 abstract "Microneurography enables neurophysiologists to record the action potentials, from myelinated and unmyelinated efferent, and afferent nerve fibers in awakened human subjects, via tungsten microelectrodes inserted percutaneously into the peripheral nerves. Recording of postganglionic sympathetic nerve traffic has become the most common application of microneurography and has been largely used. However, microneurography is of limited use, when investigating neurological syndromes, entailing a loss of sympathetic nerve fibers/activity. In general, the technical difficulty and the invasiveness of intraneural recording continue to limit its use in the clinical investigations of autonomic disorders, but the technique remains essential for the elucidation of neural mechanisms in human autonomic pathology as well as it remains predominantly a research tool in controlled studies comparing the groups of patients/subjects. It rarely proves useful, as a diagnostic tool, in individual patients. This chapter uses two examples of neurological disorders in humans— namely, central and peripheral nerve injury —to illustrate how microneurography may contribute to the differentiation between neural and effector organ dysfunction in autonomic disorders, especially when performed in parallel, with other techniques, evaluating the autonomic nervous system." @default.
- W1569673705 created "2016-06-24" @default.
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- W1569673705 date "2002-01-01" @default.
- W1569673705 modified "2023-10-16" @default.
- W1569673705 title "Chapter 19 Microneurography may differentiate between neural and effector organ dysfunctions in autonomic disorders" @default.
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- W1569673705 doi "https://doi.org/10.1016/s1567-424x(09)70439-8" @default.
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