FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569688570> ?p ?o ?g. }

• W1569688570 endingPage "491" @default.
• W1569688570 startingPage "485" @default.
• W1569688570 abstract "The aim of the present study was to investigate the effect of membrane depolarization on ATP-induced changes in intracellular Ca2+ ([Ca2+]i) and the refilling of intracellular Ca2+ stores in thyroid follicular FRTL-5 cells. Depolarizing the cells with 50 mM K+, an amount sufficient to almost totally depolarize the cells as determined by bisoxonal, significantly reduced the ATP-induced uptake of 45Ca2+. This effect was not dependent on an enhanced efflux of Ca2+, as no difference in the ATP-induced efflux of 45Ca2+ was obtained between control cells and depolarized cells. The ATP-induced transient increase in [Ca2+]i in Fura-2 loaded cells was not altered by depolarization, whereas the ATP-induced plateau in [Ca2+]i was decreased compared with control cells. Furthermore, in cells stimulated with ATP in a Ca(2+)-free buffer, readdition of Ca2+ after the termination of the ATP response induced a decreased response in [Ca2+]i in depolarized cells. Refilling of intracellular Ca2+ stores was investigated by first stimulating the cells with noradrenaline (NA). The effect of NA was then terminated with prazosin, and the cells restimulated with ATP. In cells depolarized with high K+, the response to ATP was decreased compared with that seen in control cells. The results thus suggest that both the ATP-induced influx of extracellular Ca2+ and the refilling of intracellular Ca2+ stores is decreased in depolarized FRTL-5 cells." @default.
• W1569688570 created "2016-06-24" @default.
• W1569688570 creator A5007296827 @default.
• W1569688570 date "1991-12-01" @default.
• W1569688570 modified "2023-10-14" @default.
• W1569688570 title "Depolarization of the membrane potential decreases the ATP-induced influx of extracellular Ca²⁺and the refilling of intracellular Ca²⁺stores in rat thyroid FRTL-5 cells" @default.
• W1569688570 cites W1490783082 @default.
• W1569688570 cites W1502261731 @default.
• W1569688570 cites W1508055552 @default.
• W1569688570 cites W1520080677 @default.
• W1569688570 cites W1546078475 @default.
• W1569688570 cites W1569688570 @default.
• W1569688570 cites W1579585723 @default.
• W1569688570 cites W1585654931 @default.
• W1569688570 cites W1596708629 @default.
• W1569688570 cites W1597390857 @default.
• W1569688570 cites W1669858368 @default.
• W1569688570 cites W1775749144 @default.
• W1569688570 cites W1923263235 @default.
• W1569688570 cites W1972113530 @default.
• W1569688570 cites W1999190644 @default.
• W1569688570 cites W2001417329 @default.
• W1569688570 cites W2004403903 @default.
• W1569688570 cites W2008724578 @default.
• W1569688570 cites W2010880470 @default.
• W1569688570 cites W2020727035 @default.
• W1569688570 cites W2022551298 @default.
• W1569688570 cites W2038363731 @default.
• W1569688570 cites W2049947947 @default.
• W1569688570 cites W2059080130 @default.
• W1569688570 cites W2074183540 @default.
• W1569688570 cites W2078833535 @default.
• W1569688570 cites W2082187113 @default.
• W1569688570 cites W2090708403 @default.
• W1569688570 cites W2110041210 @default.
• W1569688570 cites W2141260882 @default.
• W1569688570 cites W2799503982 @default.
• W1569688570 doi "https://doi.org/10.1002/jcp.1041490318" @default.
• W1569688570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1744175" @default.
• W1569688570 hasPublicationYear "1991" @default.
• W1569688570 type Work @default.
• W1569688570 sameAs 1569688570 @default.
• W1569688570 citedByCount "16" @default.
• W1569688570 countsByYear W15696885702012 @default.
• W1569688570 countsByYear W15696885702013 @default.
• W1569688570 countsByYear W15696885702014 @default.
• W1569688570 crossrefType "journal-article" @default.
• W1569688570 hasAuthorship W1569688570A5007296827 @default.
• W1569688570 hasConcept C12554922 @default.
• W1569688570 hasConcept C178790620 @default.
• W1569688570 hasConcept C181911157 @default.
• W1569688570 hasConcept C185592680 @default.
• W1569688570 hasConcept C28406088 @default.
• W1569688570 hasConcept C4141045 @default.
• W1569688570 hasConcept C519063684 @default.
• W1569688570 hasConcept C55493867 @default.
• W1569688570 hasConcept C79879829 @default.
• W1569688570 hasConcept C86803240 @default.
• W1569688570 hasConcept C95444343 @default.
• W1569688570 hasConceptScore W1569688570C12554922 @default.
• W1569688570 hasConceptScore W1569688570C178790620 @default.
• W1569688570 hasConceptScore W1569688570C181911157 @default.
• W1569688570 hasConceptScore W1569688570C185592680 @default.
• W1569688570 hasConceptScore W1569688570C28406088 @default.
• W1569688570 hasConceptScore W1569688570C4141045 @default.
• W1569688570 hasConceptScore W1569688570C519063684 @default.
• W1569688570 hasConceptScore W1569688570C55493867 @default.
• W1569688570 hasConceptScore W1569688570C79879829 @default.
• W1569688570 hasConceptScore W1569688570C86803240 @default.
• W1569688570 hasConceptScore W1569688570C95444343 @default.
• W1569688570 hasIssue "3" @default.
• W1569688570 hasLocation W15696885701 @default.
• W1569688570 hasLocation W15696885702 @default.
• W1569688570 hasOpenAccess W1569688570 @default.
• W1569688570 hasPrimaryLocation W15696885701 @default.
• W1569688570 hasRelatedWork W1569688570 @default.
• W1569688570 hasRelatedWork W2041771357 @default.
• W1569688570 hasRelatedWork W2042545009 @default.
• W1569688570 hasRelatedWork W2068406497 @default.
• W1569688570 hasRelatedWork W2068611646 @default.
• W1569688570 hasRelatedWork W2081467872 @default.
• W1569688570 hasRelatedWork W2089210777 @default.
• W1569688570 hasRelatedWork W2097710660 @default.
• W1569688570 hasRelatedWork W2107512930 @default.
• W1569688570 hasRelatedWork W2464189757 @default.
• W1569688570 hasVolume "149" @default.
• W1569688570 isParatext "false" @default.
• W1569688570 isRetracted "false" @default.
• W1569688570 magId "1569688570" @default.
• W1569688570 workType "article" @default.