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- W1569897416 abstract "Evaluation in vitro of anexperimental antibacterial silk suture is a published article of the textile technology department.,Because of good clinical performance and low cost, silk braided surgical suture becomesone of excellent and widely used sutures. But as a kind of nature protein fiber, silk easilytrend to microbial infection. Beyond that, braided structure may increase the risk of hide ofbacteria. Hence, the project of this study is to develop a novel antibacterial silk braidedsuture. Silk braided sutures were treated with antimicrobial solution which addedantimicrobial agent ZL into 5% PCL solution. Then sutures were tested for in vitro efficacyagainst S. aureus and E. coli by a zone of inhibition assay, and sustained efficacy assay,release of antibacterial property, SEM photographs against S. aureus. Sutures withantibacterial solution exhibited distinct zones of inhibition against S. aureus and E. coli. Theyalso kept antimicrobial property against S. aureus for 7 days, which was almost equal withcoated VICRYL* Plus suture. The highest release concentration of treated suture was1.53?g/ml, which was lower than Cmax of ZL, proved the safety of antibacterial silk suture.SEM photographs gave both the change of the surface and different bacteria growthsituations on the surface before and after treating." @default.
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- W1569897416 date "2013-01-01" @default.
- W1569897416 modified "2023-10-01" @default.
- W1569897416 title "Evaluation in vitro of an experimental antibacterial silk suture" @default.
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