Matches in SemOpenAlex for { <https://semopenalex.org/work/W1569914639> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1569914639 endingPage "9562" @default.
- W1569914639 startingPage "9557" @default.
- W1569914639 abstract "In the rat testis, 7 days after hypophysectomy, the microsomal content of cytochrome P-450 decreased to a negligible level. The sodium dodecyl sulfate gel electrophoresis of the microsomal preparation did not reveal a decrease in apocytochrome P-450; however, in this preparation, heme was undetectable. The latter did not reflect decreases in the activities of the heme biosynthesis enzymes. Also, an increase in heme oxygenase activity did not appear responsible for the suppression of the cytochrome levels. The cellular basis for the depression of the cytochrome was explored by measuring the incorporation of [14C]delta-aminolevulinate into the testicular microsomal and mitochondrial hemoproteins, and determining the relative affinity of microsomal heme for the endoplasmic reticulum membranes. In comparison with the sham-operated animals, in hypophysectomized rats, the specific 14C activity of heme in mitochondrial fraction was not decreased; however, that of the microsomal fraction was markedly reduced. The latter appeared to reflect a lowered binding affinity of the apoprotein moiety of cytochrome P-450 for heme. The treatment of hypophysectomized rats with human chorionic gonadotropin partially restored the normal level of the cytochrome. It is suggested that the anterior pituitary hormones control the level of cytochrome P-450 in the testis through factors which do not involve the production of heme; rather, the control appears to involve the processes of assembly of the hemoprotein and the association of the heme molecule with the apoprotein." @default.
- W1569914639 created "2016-06-24" @default.
- W1569914639 creator A5001051903 @default.
- W1569914639 creator A5006434886 @default.
- W1569914639 date "1984-08-01" @default.
- W1569914639 modified "2023-10-14" @default.
- W1569914639 title "Dissociation of heme metabolic activities from the microsomal cytochrome P-450 turnover in testis of hypophysectomized rats." @default.
- W1569914639 cites W1487373821 @default.
- W1569914639 cites W1497013369 @default.
- W1569914639 cites W1519492614 @default.
- W1569914639 cites W1532212858 @default.
- W1569914639 cites W1591909631 @default.
- W1569914639 cites W1594596352 @default.
- W1569914639 cites W1775749144 @default.
- W1569914639 cites W1828339164 @default.
- W1569914639 cites W1878915947 @default.
- W1569914639 cites W1972178461 @default.
- W1569914639 cites W2001725885 @default.
- W1569914639 cites W2004756878 @default.
- W1569914639 cites W2011828823 @default.
- W1569914639 cites W2018549431 @default.
- W1569914639 cites W2028778467 @default.
- W1569914639 cites W203009548 @default.
- W1569914639 cites W2037078665 @default.
- W1569914639 cites W2049755442 @default.
- W1569914639 cites W2065168154 @default.
- W1569914639 cites W2072074016 @default.
- W1569914639 cites W2085945488 @default.
- W1569914639 cites W2100837269 @default.
- W1569914639 cites W2122324271 @default.
- W1569914639 cites W2205626660 @default.
- W1569914639 cites W2398944594 @default.
- W1569914639 doi "https://doi.org/10.1016/s0021-9258(17)42736-0" @default.
- W1569914639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6746660" @default.
- W1569914639 hasPublicationYear "1984" @default.
- W1569914639 type Work @default.
- W1569914639 sameAs 1569914639 @default.
- W1569914639 citedByCount "17" @default.
- W1569914639 crossrefType "journal-article" @default.
- W1569914639 hasAuthorship W1569914639A5001051903 @default.
- W1569914639 hasAuthorship W1569914639A5006434886 @default.
- W1569914639 hasBestOaLocation W15699146391 @default.
- W1569914639 hasConcept C126322002 @default.
- W1569914639 hasConcept C134018914 @default.
- W1569914639 hasConcept C181199279 @default.
- W1569914639 hasConcept C185592680 @default.
- W1569914639 hasConcept C20705724 @default.
- W1569914639 hasConcept C2776217839 @default.
- W1569914639 hasConcept C2780768313 @default.
- W1569914639 hasConcept C55493867 @default.
- W1569914639 hasConcept C71924100 @default.
- W1569914639 hasConcept C86803240 @default.
- W1569914639 hasConcept C87644729 @default.
- W1569914639 hasConceptScore W1569914639C126322002 @default.
- W1569914639 hasConceptScore W1569914639C134018914 @default.
- W1569914639 hasConceptScore W1569914639C181199279 @default.
- W1569914639 hasConceptScore W1569914639C185592680 @default.
- W1569914639 hasConceptScore W1569914639C20705724 @default.
- W1569914639 hasConceptScore W1569914639C2776217839 @default.
- W1569914639 hasConceptScore W1569914639C2780768313 @default.
- W1569914639 hasConceptScore W1569914639C55493867 @default.
- W1569914639 hasConceptScore W1569914639C71924100 @default.
- W1569914639 hasConceptScore W1569914639C86803240 @default.
- W1569914639 hasConceptScore W1569914639C87644729 @default.
- W1569914639 hasIssue "15" @default.
- W1569914639 hasLocation W15699146391 @default.
- W1569914639 hasOpenAccess W1569914639 @default.
- W1569914639 hasPrimaryLocation W15699146391 @default.
- W1569914639 hasRelatedWork W1964883950 @default.
- W1569914639 hasRelatedWork W1979114098 @default.
- W1569914639 hasRelatedWork W1995187670 @default.
- W1569914639 hasRelatedWork W2033489519 @default.
- W1569914639 hasRelatedWork W2047844916 @default.
- W1569914639 hasRelatedWork W2079401101 @default.
- W1569914639 hasRelatedWork W2177135885 @default.
- W1569914639 hasRelatedWork W2283805667 @default.
- W1569914639 hasRelatedWork W2416063718 @default.
- W1569914639 hasRelatedWork W2047477681 @default.
- W1569914639 hasVolume "259" @default.
- W1569914639 isParatext "false" @default.
- W1569914639 isRetracted "false" @default.
- W1569914639 magId "1569914639" @default.
- W1569914639 workType "article" @default.