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- W1570209469 abstract "Lactate dehydrogenase activity has been shown to increase in the normal retina and to decrease progressively in the retina of rats with inherited retinal degeneration after the third week of age. In contrast with the quantitative measurements of lactate dehydrogenase in the whole organ, an investigation of the electrophoretic and catalytic features of the enzyme has allowed a very early discrimination between normal and affected rats. On montre que l'activitéde déhydrogénase du lactate augmente dans la rétine normale et décroiˆt progressivement dans la rétine des rats dont la rétine dégenère par hérédité, après la troisième semaine d'aˆge. En opposition avec les mesures quantitatives de la déhydrogénase lactique dans l'organisme total, la recherche des caractéristiques de l'enzyme parélectrophorèse et catalyse permet une discrimination très claire entre les rats normaux et atteints. Es wurde gezeigt, dass die Lactatdehydrogenase-Aktivität nach der dritten Lebenswoche in der normalen Retina zunimmt und bei Ratten mit ererbter Degeneration immer mehr zurückgeht. Im Gegensatz zur quantitativen Bestimmung der Lactathydrogenase im ganzen Organ gestattete die Untersuchung der elektrophoretischen und katalytischen Eigenschaften der Enzyme eine sehr frühzeitige Unterscheidung zwischen normalen und geschädigten Ratten." @default.
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- W1570209469 date "1963-07-01" @default.
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- W1570209469 title "Neurochemical studies on the inherited retinal degeneration of the rat" @default.
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- W1570209469 doi "https://doi.org/10.1016/0042-6989(63)90001-4" @default.
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