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- W1570300996 abstract "This chapter focuses on the solubility phenomena occurring in body fluids. Solubility phenomena such as dissolution and precipitation reactions are the physicochemical basis of various biological processes such as gas solubilities in respiratory and photosynthetic processes, crystallization, and the incorporation of metal ions such as strontium in bone by co-precipitation and solid–solution formation. The human body contains 60% water, which is an excellent solvent for electrolytes and plasma proteins. As all cell membranes are freely permeable to water, intra- and extra-cellular fluids are generally considered to be in osmotic equilibrium. Therefore, the osmolality of the extracellular fluid is approximately equal to that of the intracellular fluid (ICF), and hence plasma osmolality is a guide to intracellular osmolality. Pathological intra- and extra-cellular calcifications are frequently initiated at the biologic membranes of mitochondria or matrix vesicles, respectively, through the interaction of phosphatase enzymes with calcium-binding phospholipids, both of which are membrane-bound. Sequestration of calcium by mitochondria is a common biochemical mechanism mediating various forms of toxic cell death. Cellular microcalcification has also been observed in a diversity of human pathologies such as vascular dementia, Alzheimer's disease, Parkinson's disease, astroglioma, and posttraumatic epilepsy." @default.
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- W1570300996 date "2007-01-01" @default.
- W1570300996 modified "2023-09-26" @default.
- W1570300996 title "Solubility and Body Fluids" @default.
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