FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1570308595> ?p ?o ?g. }

• W1570308595 endingPage "491" @default.
• W1570308595 startingPage "484" @default.
• W1570308595 abstract "Marfan syndrome is an autosomal dominant heritable disorder of the connective tissue, caused by mutations of the gene FBN1, which encodes fibrillin-1, a major component of the microfibrils of the extracellular matrix. Fibrillin-1 interacts with transforming growth factor-β (TGF-β), and dysregulated TGF-β signaling plays a major role in the development of connective tissue disease and familial aortic aneurysm and dissection, including Marfan syndrome. Losartan, an angiotensin II blocker, has the potential to reduce TGF-β signaling and is expected to be an additional therapeutic option. Clinical diagnosis is made using the Ghent nosology, which requires comprehensive patient assessment and has been proven to work well, but evaluation of some of the diagnostic criteria by a single physician is difficult and time-consuming. A Marfan clinic was established at the University of Tokyo Hospital in 2005, together with cardiologists, cardiac surgeons, pediatricians, orthopedists, and ophthalmologists in one place, for the purpose of speedy and accurate evaluation and diagnosis of Marfan syndrome. In this review, we discuss the recent progress in diagnosis and treatment of Marfan syndrome, and the characteristics of Japanese patients with Marfan syndrome." @default.
• W1570308595 created "2016-06-24" @default.
• W1570308595 creator A5019110883 @default.
• W1570308595 creator A5032400721 @default.
• W1570308595 creator A5046056907 @default.
• W1570308595 creator A5057781163 @default.
• W1570308595 creator A5069217976 @default.
• W1570308595 creator A5072205563 @default.
• W1570308595 date "2014-08-01" @default.
• W1570308595 modified "2023-10-14" @default.
• W1570308595 title "Pathophysiology and Japanese clinical characteristics in Marfan syndrome" @default.
• W1570308595 cites W1963569632 @default.
• W1570308595 cites W1966313531 @default.
• W1570308595 cites W1987891430 @default.
• W1570308595 cites W1991939616 @default.
• W1570308595 cites W1996427377 @default.
• W1570308595 cites W1998758917 @default.
• W1570308595 cites W2002491526 @default.
• W1570308595 cites W2008113954 @default.
• W1570308595 cites W2017009317 @default.
• W1570308595 cites W2018492695 @default.
• W1570308595 cites W2023431960 @default.
• W1570308595 cites W2025073474 @default.
• W1570308595 cites W2038767517 @default.
• W1570308595 cites W2044250938 @default.
• W1570308595 cites W2048498913 @default.
• W1570308595 cites W2053146170 @default.
• W1570308595 cites W2054781132 @default.
• W1570308595 cites W2055447043 @default.
• W1570308595 cites W2066270582 @default.
• W1570308595 cites W2075529332 @default.
• W1570308595 cites W2091516962 @default.
• W1570308595 cites W2101069563 @default.
• W1570308595 cites W2111700258 @default.
• W1570308595 cites W2114232003 @default.
• W1570308595 cites W2125633197 @default.
• W1570308595 cites W2128129931 @default.
• W1570308595 cites W2128168840 @default.
• W1570308595 cites W2134642866 @default.
• W1570308595 cites W2145661830 @default.
• W1570308595 cites W2146979392 @default.
• W1570308595 cites W2152350731 @default.
• W1570308595 cites W2154226809 @default.
• W1570308595 cites W2167966527 @default.
• W1570308595 doi "https://doi.org/10.1111/ped.12423" @default.
• W1570308595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24931486" @default.
• W1570308595 hasPublicationYear "2014" @default.
• W1570308595 type Work @default.
• W1570308595 sameAs 1570308595 @default.
• W1570308595 citedByCount "5" @default.
• W1570308595 countsByYear W15703085952015 @default.
• W1570308595 countsByYear W15703085952016 @default.
• W1570308595 countsByYear W15703085952017 @default.
• W1570308595 countsByYear W15703085952018 @default.
• W1570308595 crossrefType "journal-article" @default.
• W1570308595 hasAuthorship W1570308595A5019110883 @default.
• W1570308595 hasAuthorship W1570308595A5032400721 @default.
• W1570308595 hasAuthorship W1570308595A5046056907 @default.
• W1570308595 hasAuthorship W1570308595A5057781163 @default.
• W1570308595 hasAuthorship W1570308595A5069217976 @default.
• W1570308595 hasAuthorship W1570308595A5072205563 @default.
• W1570308595 hasBestOaLocation W15703085951 @default.
• W1570308595 hasConcept C126322002 @default.
• W1570308595 hasConcept C142724271 @default.
• W1570308595 hasConcept C177713679 @default.
• W1570308595 hasConcept C189165786 @default.
• W1570308595 hasConcept C2779134260 @default.
• W1570308595 hasConcept C2779980429 @default.
• W1570308595 hasConcept C2779993142 @default.
• W1570308595 hasConcept C2780561598 @default.
• W1570308595 hasConcept C2781121460 @default.
• W1570308595 hasConcept C518705261 @default.
• W1570308595 hasConcept C54355233 @default.
• W1570308595 hasConcept C71924100 @default.
• W1570308595 hasConcept C76334062 @default.
• W1570308595 hasConcept C86803240 @default.
• W1570308595 hasConceptScore W1570308595C126322002 @default.
• W1570308595 hasConceptScore W1570308595C142724271 @default.
• W1570308595 hasConceptScore W1570308595C177713679 @default.
• W1570308595 hasConceptScore W1570308595C189165786 @default.
• W1570308595 hasConceptScore W1570308595C2779134260 @default.
• W1570308595 hasConceptScore W1570308595C2779980429 @default.
• W1570308595 hasConceptScore W1570308595C2779993142 @default.
• W1570308595 hasConceptScore W1570308595C2780561598 @default.
• W1570308595 hasConceptScore W1570308595C2781121460 @default.
• W1570308595 hasConceptScore W1570308595C518705261 @default.
• W1570308595 hasConceptScore W1570308595C54355233 @default.
• W1570308595 hasConceptScore W1570308595C71924100 @default.
• W1570308595 hasConceptScore W1570308595C76334062 @default.
• W1570308595 hasConceptScore W1570308595C86803240 @default.
• W1570308595 hasIssue "4" @default.
• W1570308595 hasLocation W15703085951 @default.
• W1570308595 hasLocation W15703085952 @default.
• W1570308595 hasOpenAccess W1570308595 @default.
• W1570308595 hasPrimaryLocation W15703085951 @default.
• W1570308595 hasRelatedWork W171534330 @default.
• W1570308595 hasRelatedWork W1967542527 @default.
• W1570308595 hasRelatedWork W1991528339 @default.

• next