Matches in SemOpenAlex for { <https://semopenalex.org/work/W1570331370> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1570331370 abstract "The theory of biochemical processes needs simple but realistic models of phenomena underlying microscopic dynamics of proteins. Many experiments performed in the 1980s have demonstrated that within the protein native state, apart from usual vibrational dynamics, a rich interconformational (activated) dynamics exists. The slowness of this dynamics makes any conventional theory of chemical reactions inapplicable for description of enzymatic reactions. It is presumably a rule that it is the process of conformational relaxation, and not the details of chemical mechanism, that affects their rate. In a simple model of Protein-Machine type, applied in constructing a novel theory of enzymatic reaction, conformational dynamics is treated as a realative quasi-continuous motion of solid-like structural elements of protein. Simple and tractable formulas for the chemical relaxation time and the enzyme turnover number in the steady state conditions are found. The important result obtained is that the kinetic mechanisms close to and far from the equilibrium can differ." @default.
- W1570331370 created "2016-06-24" @default.
- W1570331370 creator A5058524818 @default.
- W1570331370 date "1994-07-28" @default.
- W1570331370 modified "2023-09-27" @default.
- W1570331370 title "Protein-Machine model of a single enzymatic reaction" @default.
- W1570331370 cites W1889077695 @default.
- W1570331370 cites W1982003938 @default.
- W1570331370 cites W2079921934 @default.
- W1570331370 hasPublicationYear "1994" @default.
- W1570331370 type Work @default.
- W1570331370 sameAs 1570331370 @default.
- W1570331370 citedByCount "0" @default.
- W1570331370 crossrefType "posted-content" @default.
- W1570331370 hasAuthorship W1570331370A5058524818 @default.
- W1570331370 hasConcept C111472728 @default.
- W1570331370 hasConcept C121332964 @default.
- W1570331370 hasConcept C121864883 @default.
- W1570331370 hasConcept C138885662 @default.
- W1570331370 hasConcept C145912823 @default.
- W1570331370 hasConcept C147597530 @default.
- W1570331370 hasConcept C15744967 @default.
- W1570331370 hasConcept C159467904 @default.
- W1570331370 hasConcept C177801218 @default.
- W1570331370 hasConcept C185592680 @default.
- W1570331370 hasConcept C186060115 @default.
- W1570331370 hasConcept C24890656 @default.
- W1570331370 hasConcept C2775981520 @default.
- W1570331370 hasConcept C2776029896 @default.
- W1570331370 hasConcept C2780586882 @default.
- W1570331370 hasConcept C55493867 @default.
- W1570331370 hasConcept C59593255 @default.
- W1570331370 hasConcept C62520636 @default.
- W1570331370 hasConcept C77805123 @default.
- W1570331370 hasConcept C86803240 @default.
- W1570331370 hasConcept C89611455 @default.
- W1570331370 hasConcept C97355855 @default.
- W1570331370 hasConceptScore W1570331370C111472728 @default.
- W1570331370 hasConceptScore W1570331370C121332964 @default.
- W1570331370 hasConceptScore W1570331370C121864883 @default.
- W1570331370 hasConceptScore W1570331370C138885662 @default.
- W1570331370 hasConceptScore W1570331370C145912823 @default.
- W1570331370 hasConceptScore W1570331370C147597530 @default.
- W1570331370 hasConceptScore W1570331370C15744967 @default.
- W1570331370 hasConceptScore W1570331370C159467904 @default.
- W1570331370 hasConceptScore W1570331370C177801218 @default.
- W1570331370 hasConceptScore W1570331370C185592680 @default.
- W1570331370 hasConceptScore W1570331370C186060115 @default.
- W1570331370 hasConceptScore W1570331370C24890656 @default.
- W1570331370 hasConceptScore W1570331370C2775981520 @default.
- W1570331370 hasConceptScore W1570331370C2776029896 @default.
- W1570331370 hasConceptScore W1570331370C2780586882 @default.
- W1570331370 hasConceptScore W1570331370C55493867 @default.
- W1570331370 hasConceptScore W1570331370C59593255 @default.
- W1570331370 hasConceptScore W1570331370C62520636 @default.
- W1570331370 hasConceptScore W1570331370C77805123 @default.
- W1570331370 hasConceptScore W1570331370C86803240 @default.
- W1570331370 hasConceptScore W1570331370C89611455 @default.
- W1570331370 hasConceptScore W1570331370C97355855 @default.
- W1570331370 hasLocation W15703313701 @default.
- W1570331370 hasOpenAccess W1570331370 @default.
- W1570331370 hasPrimaryLocation W15703313701 @default.
- W1570331370 hasRelatedWork W1977783312 @default.
- W1570331370 hasRelatedWork W1982351022 @default.
- W1570331370 hasRelatedWork W1992429000 @default.
- W1570331370 hasRelatedWork W2000619385 @default.
- W1570331370 hasRelatedWork W2019024126 @default.
- W1570331370 hasRelatedWork W2032791258 @default.
- W1570331370 hasRelatedWork W2033861348 @default.
- W1570331370 hasRelatedWork W2039354115 @default.
- W1570331370 hasRelatedWork W2040026766 @default.
- W1570331370 hasRelatedWork W2051392880 @default.
- W1570331370 hasRelatedWork W2073111054 @default.
- W1570331370 hasRelatedWork W2085973446 @default.
- W1570331370 hasRelatedWork W2090312078 @default.
- W1570331370 hasRelatedWork W2141150293 @default.
- W1570331370 hasRelatedWork W2143113504 @default.
- W1570331370 hasRelatedWork W2147718401 @default.
- W1570331370 hasRelatedWork W2488537532 @default.
- W1570331370 hasRelatedWork W2928723810 @default.
- W1570331370 hasRelatedWork W3104021938 @default.
- W1570331370 hasRelatedWork W37752822 @default.
- W1570331370 isParatext "false" @default.
- W1570331370 isRetracted "false" @default.
- W1570331370 magId "1570331370" @default.
- W1570331370 workType "article" @default.