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- W1570494654 abstract "1.1. l-Glutamine:d-fructose 6-phosphate aminotransferase (EC 2.6.1.16) was isolated and partially purified from bovine trachea. The enzyme exhibited a broad pH optima from 6.5 to 7.5.2.2. The allosteric inhibition of the enzyme by UDP-N-acetylglucosamine was investigated in detail. A Hill plot of the kinetic data indicated negative cooperativity in the presence of UDP-N-acetylglucosamine.3.3. An analogue of l-glutamine, 6-diazo-5-oxo-l-norleucine exhibited competitive inhibition with respect to l-glutamine.4.4. A discussion of these findings with reference to the regulation of hexosamine biosynthesis in the mucus-producing structures of the trachea is presented." @default.
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- W1570494654 date "1972-07-01" @default.
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- W1570494654 title "Biosynthesis of respiratory tract mucins" @default.
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- W1570494654 doi "https://doi.org/10.1016/0005-2744(72)90012-5" @default.
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