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• W1570531838 abstract "The sex pheromone system of Enterococcus faecalis was discovered by observing a clumping reaction of E. faecalis strains during conjugative transfer of plasmids. It was found that only a special type of E. faecalis plasmids, the so-called sex pheromone plasmids, are transferred via this mechanism. Various experiments, especially by the group of D. B. Clewell, led to the formulation of a model describing how the sex pheromone system works. Small linear peptides, the so-called sex pheromones, are excreted by strains not possessing the corresponding sex pheromone plasmid. Donor strains harboring the plasmid do not produce the corresponding sex pheromone; they react to the presence of the peptide by production of a plasmid-encoded adhesin, the so-called aggregation substance. This adhesin allows contact between the non-motile mating partners; after conjugative transfer of the plasmid, the former recipient possesses and replicates the new plasmid. Thereby the population of E. faecalis strains is shifted to a high percentage of donor strains. This is especially true because a donor strain will still excrete sex pheromones corresponding to plasmids it does not harbor; therefore, such a strain can also function as recipient for other sex pheromone plasmids it does not possess. Various aspects of this unique plasmid collection mechanism have been studied during the last few years. The data indicate that, with the exception of pAM373, all sex pheromone plasmids possess one DNA region which is highly similar to and codes for the adhesin. It is also becoming more and more clear that regulatory functions/proteins are not conserved between different sex pheromone plasmids. Induction of adhesin synthesis needs the action of a regulatory cascade composed of unique features; at the moment we are just beginning to understand this cascade. By sequencing the first structural gene for one of those adhesins, we realized that the aggregation substance might act also as an adhesin for eucaryotic cells, probably by interaction with integrins. At least in the case of the in vitro cultured pig kidney tubulus cell line LLC-PK1 this idea could be verified. An interesting aspect of the sex pheromone system of E. faecalis is its evolution. I will discuss the idea that two different components, both of which well might contribute to virulence of the opportunistic pathogenic bacterium, were combined in the species E. faecalis to result in this unique plasmid collection system." @default.
• W1570531838 created "2016-06-24" @default.
• W1570531838 creator A5061938879 @default.
• W1570531838 date "1994-06-01" @default.
• W1570531838 modified "2023-10-01" @default.
• W1570531838 title "The sex pheromone system of Enterococcus faecalis. More than just a plasmid-collection mechanism?" @default.
• W1570531838 cites W1484496920 @default.
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• W1570531838 cites W1527440452 @default.
• W1570531838 cites W1549924584 @default.
• W1570531838 cites W1558647939 @default.
• W1570531838 cites W1601705683 @default.
• W1570531838 cites W1664921164 @default.
• W1570531838 cites W1749002747 @default.
• W1570531838 cites W1773475230 @default.
• W1570531838 cites W1839308321 @default.
• W1570531838 cites W1891406265 @default.
• W1570531838 cites W1901904957 @default.
• W1570531838 cites W1904634031 @default.
• W1570531838 cites W1916029810 @default.
• W1570531838 cites W1946951068 @default.
• W1570531838 cites W1963513459 @default.
• W1570531838 cites W1966286149 @default.
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• W1570531838 cites W1971312898 @default.
• W1570531838 cites W1973523054 @default.
• W1570531838 cites W1978209617 @default.
• W1570531838 cites W1980595924 @default.
• W1570531838 cites W1981955549 @default.
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• W1570531838 cites W1987568997 @default.
• W1570531838 cites W1989870283 @default.
• W1570531838 cites W1995814439 @default.
• W1570531838 cites W1997061553 @default.
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• W1570531838 cites W2034964825 @default.
• W1570531838 cites W2038309221 @default.
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• W1570531838 cites W2082403665 @default.
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• W1570531838 doi "https://doi.org/10.1111/j.1432-1033.1994.tb18862.x" @default.
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