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• W1570581019 abstract "Abstract To identify important structural features in the intergenic sequences of ribosomal DNAs, the nucleotide sequence of the 18-25 S rRNA intergene region was determined in a thermophilic fungus, Thermomyces lanuginosus, and compared to that of common yeasts. While a striking sequence homology was observed in the mature ribosomal sequences, the two internal transcribed spacer regions were found to be unusually G + C rich and significantly shorter than any other organism. An extensive secondary structure could be predicted but estimates of the secondary structure did not reveal a minimum structure which is common to other species; rather, in all rDNA transcripts the intergenic regions appear organized into a secondary structure in which all of the mature rRNA junctions are localized within one domain. This suggests that a role of the internal transcribed spacer in ribosome maturation may be that of a biological spring which maintains processed sites in close proximity." @default.
• W1570581019 created "2016-06-24" @default.
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• W1570581019 date "1987-06-01" @default.
• W1570581019 modified "2023-09-28" @default.
• W1570581019 title "Nucleotide sequence of the 18-25 S ribosomal RNA intergenic region from a thermophile, Thermomyces lanuginosus." @default.
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• W1570581019 doi "https://doi.org/10.1016/s0021-9258(18)47597-7" @default.
• W1570581019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3584125" @default.
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