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• W1570632099 abstract "Summary: Purpose: We evaluated visual patterns and source localization of ictal magnetoencephalography (MEG) in patients with intractable temporal lobe epilepsy (TLE) and extratemporal epilepsy (ETE). Methods: We performed spike and seizure recording simultaneously with EEG and MEG on two patients with TLE and five patients with ETE. Scalp EEG was recorded from 21 channels (10‐20 international system), whereas MEG was recorded from two 37‐channel sensors. We compared ictal EEG and MEG onset, frequency, and evolution and performed MEG dipole source localization of interictal spikes and early ictal discharges and co‐registered dipoles to brain magnetic resonance imaging (MRI). We correlated dipole characteristics with intracranial EEG, surgical resection, and outcome. Results: Ictal MEG lateralized seizure onset in both TLE patients and demonstrated ictal onset, frequency, and evolution in accordance with EEG. Ictal MEG source analysis revealed tangential vertical dipoles in the anterolateral angle in one patient, and anterior dipoles with anteroposterior orientation in the other. Intracranial EEG revealed regional entorhinal seizure onset in the first patient. Both patients became seizure free after temporal lobectomy. In ETE, ictal MEG demonstrated visual patterns similar to ictal EEG and had concordant localization with interictal MEG in all five patients. Two patients underwent surgery. Ictal MEG localization was concordant with intracranial EEG in both cases. One patient had successful outcome after surgery. The second patient did not improve after limited resection and multiple subpial transections. Conclusions: Ictal MEG can demonstrate ictal onset frequency and evolution and provide useful localizing information before epilepsy surgery." @default.
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• W1570632099 date "2003-09-22" @default.
• W1570632099 modified "2023-10-05" @default.
• W1570632099 title "Ictal Magnetoencephalography in Temporal and Extratemporal Lobe Epilepsy" @default.
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• W1570632099 doi "https://doi.org/10.1046/j.1528-1157.2003.14303.x" @default.
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