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• W1570644917 abstract "Hypertrehalosemic hormone (HTH) is a neuropeptide in the adipokinetic hormone/red pigment-concentrating hormone (AKH/RPCH) family that stimulates the synthesis of trehalose, the main blood sugar of many insects. The preproHTH of the cockroach Blaberus discoidalis was cloned from the corpora cardiaca (CC), the endocrine source for HTH, and the deduced sequence and organization of preproHTH were compared with other AKH/RPCH precursors. PreproHTH mRNA was determined to be ∼0.5 kb in length as predicted by DNA sequence analysis. Northern blot analysis of the CC, ventral nerve cord, brain and fat body detected HTH-mRNA only in the CC. Levels of the HTH transcript in the CC were determined according to age, gender and mating. The HTH message was most abundant in the CC during the first several days of adult life in both sexes, then declined by 50% and were stable. HTH-mRNA levels in the CC did not respond to mating." @default.
• W1570644917 created "2016-06-24" @default.
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• W1570644917 date "1997-06-01" @default.
• W1570644917 modified "2023-09-25" @default.
• W1570644917 title "Hypertrehalosemic hormone in a cockroach: molecular cloning and expression1Note: The nucleotide sequence reported in this paper has been deposited in the GenBank data base with accession no. U35277.1" @default.
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• W1570644917 doi "https://doi.org/10.1016/s0303-7207(97)00078-6" @default.
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