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Matches in SemOpenAlex for { <https://semopenalex.org/work/W157066585> ?p ?o ?g. }

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• W157066585 abstract "The molecular chaperone heat-shock protein 70 (Hsp70) possesses immune stimulatory properties that have been employed in the preparation of anticancer vaccines. Hsp70 binds antigenic peptides in the cytoplasm of cancer cells. Hsp70 thus serves as a convenient, non-discriminating transporter of antigens and can protect the peptides during internalization by APC and cross presentation to T lymphocytes. We describe a method for purifying Hsp70-peptide complexes that can be used to prepare molecular chaperone-based vaccines, involving sequential gel filtration, ion exchange, and affinity chromatography." @default.
• W157066585 created "2016-06-24" @default.
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• W157066585 date "2012-10-29" @default.
• W157066585 modified "2023-09-26" @default.
• W157066585 title "Purification, Preparation, and Use of Chaperone–Peptide Complexes for Tumor Immunotherapy" @default.
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• W157066585 doi "https://doi.org/10.1007/978-1-62703-218-6_17" @default.
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