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- W1570682068 abstract "The suppression of lepra reaction by cortisone (del Pozo and Gonzalez Ochoa, 1952) as an immediate and striking effect, opened several questions in relation to the evaluation of cortisone as a therapeutic agent in lepra patients. Two v problems had to be solved before the systematic use of cortisone could be advised in the clinical management of patients with the acute reaction. First, if cortisone itself could be noxious to the natural course of the disease; second, if the suppression of the lepra reaction could be considered unfavorable from / v the standpoint of the individual's resistance to infection. Many other collateral problems were left unsolved in the preliminary trials of this steroid in leprosy, (for instance, a possible reduction in the initial benefit produced by the first doses, the secondary physiological effects of cortisone, and an interference with the therapeutic properties of the anti-leprosy drugs, etc.) A long assay of cortisone in lepra patients was required. The present report refers to the treatment of a group of lepromatous patients continuously treated with cortisone during a period of one year." @default.
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- W1570682068 date "1955-01-01" @default.
- W1570682068 modified "2023-09-27" @default.
- W1570682068 title "Long Term Treatment of Leprosy with Cortisone11Instituto de Salubridad y Enfermedades Tropicales, México, D. F." @default.
- W1570682068 cites W2516856327 @default.
- W1570682068 doi "https://doi.org/10.1038/jid.1955.7" @default.
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