FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W157068544> ?p ?o ?g. }

• W157068544 endingPage "40" @default.
• W157068544 startingPage "1530" @default.
• W157068544 abstract "To evaluate the role that delayed-type hypersensitivity (DTH) and cytotoxic T lymphocyte responses play in a murine model of orthotopic corneal allograft transplantation.Corneal transplantation was performed by grafting C57BL/6 donor corneas into BALB/c corneal beds. After transplantation, the mice were observed by slit lamp biomicroscopy on a weekly basis and graded for signs of graft rejection and delayed-type hypersensitivity (DTH) and cytotoxic T lymphocyte (CTL) responses to donor alloantigens assessed at selected times after grafting.It was determined that between 40% and 65% of BALB/c mice rejected C57BL/6 corneas by 8 weeks after engraftment. Mice with opacity scores > 2 demonstrated significantly greater DTH responses than did mice with opacity scores < 2 at 2, 3, and 4 weeks after engraftment. After 4 weeks, the DTH responses for all groups were essentially the same as for naive BALB/c mice. The DTH responses were specific for C57BL/6 alloantigens and are primarily directed against non-major histocompatibility complex (MHC) C57BL/6 alloantigens and are primarily directed against non-major histocompatibility complex C57BL/6 alloantigens, as evidenced by the ability of B10.D2 cells to elicit DTH responses whereas C.B10-H-2b cells did not. However, although BALB/c mice engrafted with C57BL/6 tail skin demonstrated significantly greater CTL activity than naive BALB/c mice, there was no significant difference in CTL activity between BALB/c mice whose C57BL/6 corneal allografts displayed opacity scores greater than (rejected) or less than (accepted) 2.The mechanism whereby corneal allografts in this strain combination are rejected is best associated with the ability to generate strong DTH responses and not CTL activity. This DTH response also demonstrates alloantigen specificity and appears to be primarily directed against the non-MHC component of the corneal transplant." @default.
• W157068544 created "2016-06-24" @default.
• W157068544 creator A5022918429 @default.
• W157068544 creator A5045207583 @default.
• W157068544 creator A5051060008 @default.
• W157068544 date "1995-07-01" @default.
• W157068544 modified "2023-10-17" @default.
• W157068544 title "T-cell mediated responses in a murine model of orthotopic corneal transplantation." @default.
• W157068544 cites W114138241 @default.
• W157068544 cites W1486085957 @default.
• W157068544 cites W1507999061 @default.
• W157068544 cites W1527992196 @default.
• W157068544 cites W1544490832 @default.
• W157068544 cites W1563525861 @default.
• W157068544 cites W1599245394 @default.
• W157068544 cites W1610376024 @default.
• W157068544 cites W1755741277 @default.
• W157068544 cites W1853022482 @default.
• W157068544 cites W1884067458 @default.
• W157068544 cites W197764648 @default.
• W157068544 cites W1995368448 @default.
• W157068544 cites W2006625569 @default.
• W157068544 cites W2025734854 @default.
• W157068544 cites W2029268528 @default.
• W157068544 cites W2036970746 @default.
• W157068544 cites W2073096938 @default.
• W157068544 cites W2102942510 @default.
• W157068544 cites W2112036147 @default.
• W157068544 cites W2169994044 @default.
• W157068544 cites W2310951129 @default.
• W157068544 cites W2341226735 @default.
• W157068544 cites W2418430042 @default.
• W157068544 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7601633" @default.
• W157068544 hasPublicationYear "1995" @default.
• W157068544 type Work @default.
• W157068544 sameAs 157068544 @default.
• W157068544 citedByCount "43" @default.
• W157068544 countsByYear W1570685442012 @default.
• W157068544 countsByYear W1570685442013 @default.
• W157068544 countsByYear W1570685442014 @default.
• W157068544 countsByYear W1570685442016 @default.
• W157068544 countsByYear W1570685442017 @default.
• W157068544 countsByYear W1570685442018 @default.
• W157068544 countsByYear W1570685442021 @default.
• W157068544 countsByYear W1570685442022 @default.
• W157068544 crossrefType "journal-article" @default.
• W157068544 hasAuthorship W157068544A5022918429 @default.
• W157068544 hasAuthorship W157068544A5045207583 @default.
• W157068544 hasAuthorship W157068544A5051060008 @default.
• W157068544 hasConcept C118487528 @default.
• W157068544 hasConcept C126322002 @default.
• W157068544 hasConcept C141071460 @default.
• W157068544 hasConcept C147483822 @default.
• W157068544 hasConcept C147969180 @default.
• W157068544 hasConcept C154317977 @default.
• W157068544 hasConcept C167672396 @default.
• W157068544 hasConcept C188280979 @default.
• W157068544 hasConcept C202751555 @default.
• W157068544 hasConcept C202965653 @default.
• W157068544 hasConcept C203014093 @default.
• W157068544 hasConcept C207936829 @default.
• W157068544 hasConcept C2776090121 @default.
• W157068544 hasConcept C2776882836 @default.
• W157068544 hasConcept C2777750529 @default.
• W157068544 hasConcept C2778740727 @default.
• W157068544 hasConcept C2779456560 @default.
• W157068544 hasConcept C2780686511 @default.
• W157068544 hasConcept C2911091166 @default.
• W157068544 hasConcept C3017924640 @default.
• W157068544 hasConcept C48556533 @default.
• W157068544 hasConcept C55493867 @default.
• W157068544 hasConcept C71924100 @default.
• W157068544 hasConcept C86803240 @default.
• W157068544 hasConcept C8891405 @default.
• W157068544 hasConceptScore W157068544C118487528 @default.
• W157068544 hasConceptScore W157068544C126322002 @default.
• W157068544 hasConceptScore W157068544C141071460 @default.
• W157068544 hasConceptScore W157068544C147483822 @default.
• W157068544 hasConceptScore W157068544C147969180 @default.
• W157068544 hasConceptScore W157068544C154317977 @default.
• W157068544 hasConceptScore W157068544C167672396 @default.
• W157068544 hasConceptScore W157068544C188280979 @default.
• W157068544 hasConceptScore W157068544C202751555 @default.
• W157068544 hasConceptScore W157068544C202965653 @default.
• W157068544 hasConceptScore W157068544C203014093 @default.
• W157068544 hasConceptScore W157068544C207936829 @default.
• W157068544 hasConceptScore W157068544C2776090121 @default.
• W157068544 hasConceptScore W157068544C2776882836 @default.
• W157068544 hasConceptScore W157068544C2777750529 @default.
• W157068544 hasConceptScore W157068544C2778740727 @default.
• W157068544 hasConceptScore W157068544C2779456560 @default.
• W157068544 hasConceptScore W157068544C2780686511 @default.
• W157068544 hasConceptScore W157068544C2911091166 @default.
• W157068544 hasConceptScore W157068544C3017924640 @default.
• W157068544 hasConceptScore W157068544C48556533 @default.
• W157068544 hasConceptScore W157068544C55493867 @default.
• W157068544 hasConceptScore W157068544C71924100 @default.
• W157068544 hasConceptScore W157068544C86803240 @default.

• next