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• W1570932923 abstract "This chapter discusses 27 new molecular entities (NMEs) which were in manufactured in the year 2007. The anticancer sector has garnered competition for Merck's Gardasil® vaccine against human papillomavirus (HPV) with the introduction of GlaxoSmithKline's Cervarix® for the prevention of HPV-induced cervical cancer and infections. The anti-infective arena contributed four NMEs, a mixed composition drug, and three vaccines Selzentry™ (maraviroc), Isentress™ (raltegravir), Geninax® (garenoxacin), and Altabax™ (retapamulin). The CNS field was represented by the entry of three new drugs Vyvanse™ (lisdexamfetamine), Exelon® Patch, and Lyrica® (pregabalin). The cardiovascular domain welcomed two NMEs Tekturna® (aliskiren) and Letairis™ (ambrisentan). In the respiratory area, two new drugs emerged. Veramyst™ (fluticasone furoate) and Brovana™ (arformoterol). Concerning endocrine diseases, diabetes patients received two new options Galvus® (vildagliptin) and Janumet™. The CNS field was represented by the entry of three new drugs and new indications for existing drugs. Joining other marketed amphetamine and methylphenidate formulations for the treatment of attention-deficit/hyperactivity disorder (ADHD), Vyvanse™ (lisdexamfetamine) is a prodrug of D-amphetamine that boasts reduced abuse potential with an extended-release benefit. The cardiovascular domain welcomed two NMEs Tekturna® (aliskiren) and Ambrisentan (Pulmonary Arterial Hypertension). In the respiratory area, two new drugs emerged Veramyst™ (fluticasone furoate) and Brovana™ (arformoterol). Concerning endocrine diseases, diabetes patients received Galvus® (vildagliptin). The metabolic section saw the introduction of the only new biologic product of the year. Solirist (eculizumab) is a humanized monoclonal antibody targeting the C5 protein of the complement system whose cleavage is instrumental to the destructive inflammatory cascade culminating in hemolytic anemia." @default.
• W1570932923 created "2016-06-24" @default.
• W1570932923 creator A5038344266 @default.
• W1570932923 creator A5062398232 @default.
• W1570932923 date "2008-01-01" @default.
• W1570932923 modified "2023-09-23" @default.
• W1570932923 title "To Market, To Market — 2007" @default.
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• W1570932923 doi "https://doi.org/10.1016/s0065-7743(08)00025-0" @default.
• W1570932923 hasPublicationYear "2008" @default.
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