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- W1570986866 abstract "Abstract: Inorganic arsenic is a potent human carcinogen and general toxicant. More than one hundred million people are exposed to elevated concentrations, mainly via drinking water, but also via industrial emissions. Arsenic is metabolized via methylation and reduction reactions, methylarsonic acid and dimethylarsinic acid being the main metabolites excreted in urine. Both inorganic arsenic and its methylated metabolites easily pass the placenta and both experimental and human studies have shown increased risk of impaired foetal growth and increased foetal loss. Recent studies indicate that prenatal arsenic exposure also increases the risk of adverse effects during early childhood. There is a growing body of evidence that the intrauterine or early childhood exposure to arsenic also induces changes that will become apparent much later in life. One epidemiological study indicated that exposure to arsenic in drinking water during early childhood or in utero was associated with an increased mortality in young adults from both malignant and non-malignant lung disease. Furthermore, a series of experimental animal studies provide strong support for late effects of arsenic, including various forms of cancer, following intrauterine arsenic exposure. The involved modes of action include epigenetic effects, mainly via DNA hypomethylation, endocrine effects (most classes of steroid hormones), immune suppression, neurotoxicity, and interaction with enzymes critical for foetal development and programming." @default.
- W1570986866 created "2016-06-24" @default.
- W1570986866 creator A5091468032 @default.
- W1570986866 date "2008-01-22" @default.
- W1570986866 modified "2023-09-30" @default.
- W1570986866 title "Health Effects of Early Life Exposure to Arsenic" @default.
- W1570986866 cites W117048748 @default.
- W1570986866 cites W1505133202 @default.
- W1570986866 cites W1511060765 @default.
- W1570986866 cites W1867300354 @default.
- W1570986866 cites W1889337372 @default.
- W1570986866 cites W1895354952 @default.
- W1570986866 cites W1963696871 @default.
- W1570986866 cites W1965628135 @default.
- W1570986866 cites W1966384484 @default.
- W1570986866 cites W1968409447 @default.
- W1570986866 cites W1968769931 @default.
- W1570986866 cites W1973297589 @default.
- W1570986866 cites W1975639741 @default.
- W1570986866 cites W1976086749 @default.
- W1570986866 cites W1980937230 @default.
- W1570986866 cites W1980965029 @default.
- W1570986866 cites W1982584346 @default.
- W1570986866 cites W1985493312 @default.
- W1570986866 cites W1993532042 @default.
- W1570986866 cites W1994194752 @default.
- W1570986866 cites W1996508594 @default.
- W1570986866 cites W1999788446 @default.
- W1570986866 cites W2002991516 @default.
- W1570986866 cites W2003024378 @default.
- W1570986866 cites W2006169808 @default.
- W1570986866 cites W2009317934 @default.
- W1570986866 cites W2013833448 @default.
- W1570986866 cites W2016424609 @default.
- W1570986866 cites W2016902028 @default.
- W1570986866 cites W2022831448 @default.
- W1570986866 cites W2022921500 @default.
- W1570986866 cites W2035756657 @default.
- W1570986866 cites W2038187262 @default.
- W1570986866 cites W2042249627 @default.
- W1570986866 cites W2042614655 @default.
- W1570986866 cites W2046155936 @default.
- W1570986866 cites W2047454507 @default.
- W1570986866 cites W2047969297 @default.
- W1570986866 cites W2049177810 @default.
- W1570986866 cites W2050375130 @default.
- W1570986866 cites W2051384809 @default.
- W1570986866 cites W2052305135 @default.
- W1570986866 cites W2053798667 @default.
- W1570986866 cites W2054781010 @default.
- W1570986866 cites W2061001587 @default.
- W1570986866 cites W2080013193 @default.
- W1570986866 cites W2080723247 @default.
- W1570986866 cites W2081995492 @default.
- W1570986866 cites W2084767711 @default.
- W1570986866 cites W2091963409 @default.
- W1570986866 cites W2094734398 @default.
- W1570986866 cites W2094745847 @default.
- W1570986866 cites W2101624738 @default.
- W1570986866 cites W2102219401 @default.
- W1570986866 cites W2102311939 @default.
- W1570986866 cites W2105360146 @default.
- W1570986866 cites W2106380683 @default.
- W1570986866 cites W2106917119 @default.
- W1570986866 cites W2108638666 @default.
- W1570986866 cites W2109114226 @default.
- W1570986866 cites W2110859074 @default.
- W1570986866 cites W2119322375 @default.
- W1570986866 cites W2120771685 @default.
- W1570986866 cites W2125922899 @default.
- W1570986866 cites W2132017547 @default.
- W1570986866 cites W2134238156 @default.
- W1570986866 cites W2135496473 @default.
- W1570986866 cites W2140121626 @default.
- W1570986866 cites W2142047783 @default.
- W1570986866 cites W2146282065 @default.
- W1570986866 cites W2150076336 @default.
- W1570986866 cites W2152784658 @default.
- W1570986866 cites W2157118370 @default.
- W1570986866 cites W2157299842 @default.
- W1570986866 cites W2167076734 @default.
- W1570986866 cites W2167096102 @default.
- W1570986866 cites W2315353002 @default.
- W1570986866 cites W4234891782 @default.
- W1570986866 cites W4241222751 @default.
- W1570986866 cites W78137650 @default.
- W1570986866 doi "https://doi.org/10.1111/j.1742-7843.2007.00168.x" @default.
- W1570986866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18226075" @default.
- W1570986866 hasPublicationYear "2008" @default.
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