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- W1571062015 abstract "Adrenal cortical carcinoma (ACC) is a rare cancer that poses a number of management challenges due to the limited number of effective systemic treatments. Complete surgical resection offers the best chance of long-term survival. However, despite complete resection, ACC is associated with high recurrence rates. This review will discuss the management of recurrent ACC in adults following complete surgical resection. Management should take place in a specialist center and treatment decisions must consider the individual tumor biology of each case of recurrence. Given the fact that ACC commonly recurs, management to prevent recurrence should be considered from initial diagnosis with the use of adjuvant mitotane. Close follow up with clinical examination and imaging is important for early detection of recurrent disease. Locoregional recurrence may be isolated, and repeat surgical resection should be considered along with mitotane. The use of radiotherapy in ACC remains controversial. Systemic recurrence most often involves liver, pulmonary, and bone metastasis and is usually managed with mitotane, with or without combination chemotherapy. There is a limited role for surgical resection in systemic recurrence in selected patients. In all patients with recurrent disease, control of excessive hormone production is an important part of management. Despite intensive management of recurrent ACC, treatment failure is common and the use of clinical trials and novel treatment is an important part of management." @default.
- W1571062015 created "2016-06-24" @default.
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- W1571062015 date "2013-06-01" @default.
- W1571062015 modified "2023-10-01" @default.
- W1571062015 title "Current management options for recurrent adrenocortical carcinoma" @default.
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- W1571062015 cites W1964132313 @default.
- W1571062015 cites W1965293262 @default.
- W1571062015 cites W1967352082 @default.
- W1571062015 cites W1967949880 @default.
- W1571062015 cites W1978608178 @default.
- W1571062015 cites W1980615409 @default.
- W1571062015 cites W1983091335 @default.
- W1571062015 cites W1986369956 @default.
- W1571062015 cites W1988688032 @default.
- W1571062015 cites W1989143788 @default.
- W1571062015 cites W1991016861 @default.
- W1571062015 cites W1991690093 @default.
- W1571062015 cites W1992592882 @default.
- W1571062015 cites W1992760930 @default.
- W1571062015 cites W1993215090 @default.
- W1571062015 cites W2007474279 @default.
- W1571062015 cites W2012899953 @default.
- W1571062015 cites W2016982939 @default.
- W1571062015 cites W2023067758 @default.
- W1571062015 cites W2027230133 @default.
- W1571062015 cites W2031590233 @default.
- W1571062015 cites W2032999587 @default.
- W1571062015 cites W2035178765 @default.
- W1571062015 cites W2039860243 @default.
- W1571062015 cites W2040642687 @default.
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- W1571062015 cites W2044178604 @default.
- W1571062015 cites W2045466543 @default.
- W1571062015 cites W2050111607 @default.
- W1571062015 cites W2054666781 @default.
- W1571062015 cites W2055827085 @default.
- W1571062015 cites W2059779476 @default.
- W1571062015 cites W2065685530 @default.
- W1571062015 cites W2066193070 @default.
- W1571062015 cites W2066923659 @default.
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- W1571062015 cites W2072709644 @default.
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- W1571062015 cites W2079874148 @default.
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- W1571062015 cites W2080838501 @default.
- W1571062015 cites W2084654797 @default.
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- W1571062015 doi "https://doi.org/10.2147/ott.s34956" @default.
- W1571062015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3681406" @default.
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