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- W1572201892 abstract "The liver is unique in that it responds to physical or chemical injury by the process of regeneration. The benign and malignant natures of hepatic tumors and tumor-like lesions are classified in the chapter. Hepatocellular adenoma and local nodular hyperplasia are the two most common benign neoplasms of the liver, occurring predominantly in women. Primary liver carcinomas are classified as hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma, and cholangiocarcinoma. The biological behavior and clinicopathologic features of the third type show that it is not simply a combination of the first two types. In fact, consistent differences of genetic alterations have been observed at different loci in HCC and intrahepatic cholangiocarcinoma. The chapter focuses on HCC, because HCC amounts to ∼90% of primary liver cancer. Carcinogenesis is a multiple-step process with molecular events in each stage of disease progression. The development of HCC is an example of the multistage process. Although early HCC is curable in most cases by surgical resectioning, the asymptomatic feature of HCC progression results in poor prognosis and a 5 year survival." @default.
- W1572201892 created "2016-06-24" @default.
- W1572201892 creator A5005071483 @default.
- W1572201892 date "2005-01-01" @default.
- W1572201892 modified "2023-09-24" @default.
- W1572201892 title "Liver Carcinoma" @default.
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