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- W1572208210 abstract "We here describe the study-design major findings from the neuropathological component of the Medical Research Council Cognitive Function and Aging Study (MRC CFAS). MRC CFAS is a population-representative study of aging and health including more than 18000 participants at baseline. More than 500 brain donations were accrued to date and have been subjected to comprehensive pathological assessment. This resource enables a thorough epidemiological description of the neuropathology associated with dementia in the UK. Results to date reveal a high prevalence of mixed Alzheimer and vascular pathology, a significant population who die with dementia but with a more limited pathological burden than is traditionally associated with dementia, and a group who die with a significant pathological burden yet remained cognitively intact until death. This dissociation between pathology and dementia increases with increasing age. Further studies have described the distribution and etiology of neurodegenerative disease in the population, and determined pathological correlates of cognitive impairment and dementia. Brain donation programs linked to epidemiological studies provide an invaluable resource for describing the pathological correlates of dementia in a way that is representative of the population, thereby identifying targets for and assessing the likely effect of therapeutic and preventive interventions." @default.
- W1572208210 created "2016-06-24" @default.
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- W1572208210 date "2011-07-01" @default.
- W1572208210 modified "2023-10-18" @default.
- W1572208210 title "Epidemiological Neuropathology: The MRC Cognitive Function and Aging Study Experience" @default.
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- W1572208210 cites W1967823816 @default.
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- W1572208210 cites W1968324269 @default.
- W1572208210 cites W1972340735 @default.
- W1572208210 cites W1974433124 @default.
- W1572208210 cites W1978836458 @default.
- W1572208210 cites W1983166842 @default.
- W1572208210 cites W1987466993 @default.
- W1572208210 cites W1990752558 @default.
- W1572208210 cites W1998088268 @default.
- W1572208210 cites W2002292126 @default.
- W1572208210 cites W2005734066 @default.
- W1572208210 cites W2012987313 @default.
- W1572208210 cites W2015020748 @default.
- W1572208210 cites W2026060908 @default.
- W1572208210 cites W2035416600 @default.
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- W1572208210 cites W2073449985 @default.
- W1572208210 cites W2075091034 @default.
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- W1572208210 cites W2082004177 @default.
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- W1572208210 cites W2102572922 @default.
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- W1572208210 cites W2147599271 @default.
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- W1572208210 cites W2157617823 @default.
- W1572208210 cites W2158658606 @default.
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- W1572208210 doi "https://doi.org/10.3233/jad-2011-091402" @default.
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