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- W1572845999 abstract "Abstract Human interferon binds to concanavalin A-agarose at high ionic strength (1.0 m NaCl) and cannot be readily displaced from the column with 0.1 m α-methyl-d-mannopyranoside. A partial recovery of interferon activity, with a protracted elution profile, was obtained with ethylene glycol, a polarity reducing agent. Complete recovery of activity, with a sharp elution profile, was obtained by the combined action of sugar and ethylene glycol. Apparently, the binding of human interferon to concanavalin A-agarose is due to both carbohydrate recognition and hydrophobic interaction." @default.
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- W1572845999 date "1974-10-01" @default.
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- W1572845999 title "Hydrophobic Interaction of Human Interferon with Concanavalin A-Agarose" @default.
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- W1572845999 doi "https://doi.org/10.1016/s0021-9258(19)42261-8" @default.
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