FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1573327939> ?p ?o ?g. }

• W1573327939 endingPage "7511" @default.
• W1573327939 startingPage "7504" @default.
• W1573327939 abstract "Abstract Although the antibacterial effects of Abs are well studied in in vitro systems, the in vivo effects of Abs cannot always be accurately predicted. Complicated cross-talk between different effector functions of Abs and various arms of the immune system can affect their activities in vivo. Using the mouse respiratory pathogen Bordetella bronchiseptica, we examined the mechanisms of Ab-mediated clearance of bacteria from the respiratory tract. Interestingly, although TLR4 was not necessary for protective immunity following infection, it was required for rapid bacterial clearance in mice that were vaccinated or adoptively transferred Abs. TLR4 was important for the rapid recruitment of neutrophils that are necessary for Ab-mediated bacterial clearance via a mechanism that requires both FcγR and CR3. These data are consistent with a model in which TLR4-mediated inflammatory responses aid in the recruitment of neutrophils, which phagocytose Ab- and complement-opsonized bacteria via FcγRs and CR3. Although pattern recognition receptors are known to be involved in innate immunity and the generation of adaptive immunity, their contributions to specific adaptive immune functions should be considered in ongoing efforts to improve vaccine-induced protective immunity." @default.
• W1573327939 created "2016-06-24" @default.
• W1573327939 creator A5039818507 @default.
• W1573327939 creator A5044641921 @default.
• W1573327939 creator A5064761262 @default.
• W1573327939 creator A5083110437 @default.
• W1573327939 creator A5087414453 @default.
• W1573327939 date "2005-12-01" @default.
• W1573327939 modified "2023-10-16" @default.
• W1573327939 title "The Complex Mechanism of Antibody-Mediated Clearance of <i>Bordetella</i> from the Lungs Requires TLR4" @default.
• W1573327939 cites W121687570 @default.
• W1573327939 cites W1483162601 @default.
• W1573327939 cites W1505851442 @default.
• W1573327939 cites W1543657751 @default.
• W1573327939 cites W1607469053 @default.
• W1573327939 cites W1967821522 @default.
• W1573327939 cites W1972108403 @default.
• W1573327939 cites W1983940041 @default.
• W1573327939 cites W1988891943 @default.
• W1573327939 cites W1997370219 @default.
• W1573327939 cites W2003533722 @default.
• W1573327939 cites W2017663793 @default.
• W1573327939 cites W2025528576 @default.
• W1573327939 cites W2037871512 @default.
• W1573327939 cites W2052954853 @default.
• W1573327939 cites W2066861122 @default.
• W1573327939 cites W2106139392 @default.
• W1573327939 cites W2108105410 @default.
• W1573327939 cites W2115726166 @default.
• W1573327939 cites W2125766883 @default.
• W1573327939 cites W2127427276 @default.
• W1573327939 cites W2128455422 @default.
• W1573327939 cites W2131041278 @default.
• W1573327939 cites W2132239186 @default.
• W1573327939 cites W2132241692 @default.
• W1573327939 cites W2139867627 @default.
• W1573327939 cites W2142866987 @default.
• W1573327939 cites W2144689930 @default.
• W1573327939 cites W2145708021 @default.
• W1573327939 cites W2154271415 @default.
• W1573327939 cites W2159613168 @default.
• W1573327939 cites W2160319303 @default.
• W1573327939 cites W2162726394 @default.
• W1573327939 cites W2164966842 @default.
• W1573327939 cites W2168209015 @default.
• W1573327939 cites W2398001552 @default.
• W1573327939 cites W315197452 @default.
• W1573327939 cites W4250688128 @default.
• W1573327939 doi "https://doi.org/10.4049/jimmunol.175.11.7504" @default.
• W1573327939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16301658" @default.
• W1573327939 hasPublicationYear "2005" @default.
• W1573327939 type Work @default.
• W1573327939 sameAs 1573327939 @default.
• W1573327939 citedByCount "39" @default.
• W1573327939 countsByYear W15733279392012 @default.
• W1573327939 countsByYear W15733279392013 @default.
• W1573327939 countsByYear W15733279392015 @default.
• W1573327939 countsByYear W15733279392016 @default.
• W1573327939 countsByYear W15733279392019 @default.
• W1573327939 countsByYear W15733279392021 @default.
• W1573327939 countsByYear W15733279392023 @default.
• W1573327939 crossrefType "journal-article" @default.
• W1573327939 hasAuthorship W1573327939A5039818507 @default.
• W1573327939 hasAuthorship W1573327939A5044641921 @default.
• W1573327939 hasAuthorship W1573327939A5064761262 @default.
• W1573327939 hasAuthorship W1573327939A5083110437 @default.
• W1573327939 hasAuthorship W1573327939A5087414453 @default.
• W1573327939 hasBestOaLocation W15733279391 @default.
• W1573327939 hasConcept C136449434 @default.
• W1573327939 hasConcept C150903083 @default.
• W1573327939 hasConcept C159654299 @default.
• W1573327939 hasConcept C160448771 @default.
• W1573327939 hasConcept C170493617 @default.
• W1573327939 hasConcept C193419808 @default.
• W1573327939 hasConcept C203014093 @default.
• W1573327939 hasConcept C207001950 @default.
• W1573327939 hasConcept C2776070231 @default.
• W1573327939 hasConcept C2777107318 @default.
• W1573327939 hasConcept C2779341262 @default.
• W1573327939 hasConcept C51785407 @default.
• W1573327939 hasConcept C523546767 @default.
• W1573327939 hasConcept C54355233 @default.
• W1573327939 hasConcept C55493867 @default.
• W1573327939 hasConcept C86803240 @default.
• W1573327939 hasConcept C8891405 @default.
• W1573327939 hasConcept C89372155 @default.
• W1573327939 hasConcept C89423630 @default.
• W1573327939 hasConceptScore W1573327939C136449434 @default.
• W1573327939 hasConceptScore W1573327939C150903083 @default.
• W1573327939 hasConceptScore W1573327939C159654299 @default.
• W1573327939 hasConceptScore W1573327939C160448771 @default.
• W1573327939 hasConceptScore W1573327939C170493617 @default.
• W1573327939 hasConceptScore W1573327939C193419808 @default.
• W1573327939 hasConceptScore W1573327939C203014093 @default.
• W1573327939 hasConceptScore W1573327939C207001950 @default.
• W1573327939 hasConceptScore W1573327939C2776070231 @default.
• W1573327939 hasConceptScore W1573327939C2777107318 @default.
• W1573327939 hasConceptScore W1573327939C2779341262 @default.

• next