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- W1573485677 abstract "The studies presented in this thesis were designed to investigate whether the decline in parasympathetic responsiveness to stress in aged rats can be generalized for various (environmental) challenges. In addition, the contribution of this reduced vagal responsiveness in aged animals to autonomic dysbalance was determined. Finally, considerable attention was paid to the role of arninergic and vasopressinergic systems in the age-related reduction of vagal responses. The results show that in aged rats parasympathetic responsiveness to a variety of challenges is reduced. However, sympathetic responsiveness is reduced as well. Therefore, autonomic output remains in balance during mild emotional stress situations. Enhancement of the aminergic “state” reinstates the vagal responsiveness to emotional but not to metabolic challenges in aged rats. Systemic administration of vasopressin improves and prolongs both the behavioral and vagal emotional stress responses in rats but only until late-adult age (14months) is reached." @default.
- W1573485677 created "2016-06-24" @default.
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- W1573485677 date "1992-04-03" @default.
- W1573485677 modified "2023-09-23" @default.
- W1573485677 title "The parasympathetic responsiveness in young and aged rats : Involvement of aminergic and vasopressinergic mechanisms" @default.
- W1573485677 hasPublicationYear "1992" @default.
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