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• W1573751702 abstract "A systems biology problem of reconstructing gene regulatory network from time-course gene expression microarray data via network component analysis (NCA) is investigated in this paper. Inspired by the idea that each column of the connectivity matrix can be estimated independently, we try to propose a fast and stable convex approach for nonnegative NCA (nnNCA). Compared with the existing method, our new method reduces the computational cost substantially, whereas maintains a reasonable accuracy. Both the simulation results and experimental results demonstrate the effectiveness of our method." @default.
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• W1573751702 date "2009-01-01" @default.
• W1573751702 modified "2023-10-01" @default.
• W1573751702 title "An Efficient Convex Nonnegative Network Component Analysis for Gene Regulatory Network Reconstruction" @default.
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• W1573751702 doi "https://doi.org/10.1007/978-3-642-04031-3_6" @default.
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