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• W1573886305 abstract "As it has been mentioned in the previous chapters, Angina pectoris, commonly known as angina, is severe chest pain and discomfort due to myocardial ischemia. A lack of blood, hence a lack of oxygen supply for heart muscle, will cause this pain which can be because of narrowed and blocked coronary arteries. In other words, angina can be assumed to play the role of a protective mechanism to signal myocardial ischemia. There are different kinds of angina. Stable, unstable, Prinzmetal’s or variant angina and latterly discovered type called microvascular angina which is caused by small blood vessels, not artery damage. Although the amount of mortalities and morbidities of heart diseases and additionally the diagnostic techniques in this field underwent drastic improvements, still there are many patients complaining about angina pectoris mostly as a restricting pain. Due to the report of American Heart Association statistics committee and stroke statistics subcommittee in 2010, the prevalence of angina pectoris has become 9.8 million, translating to almost 30 thousand per million. This amount in Europe has been estimated to be around 20 40 thousand per million (Fox, Garcia et al. 2006; Fernandez, Tandar et al. 2010; Lioyd-Jones, Adams et al. 2010). In another study performed in US, it has been mentioned that 1 in 4 patients is experiencing angina pectoris following myocardial infarction. With regard to the annual occurrence of MI in US which is 1.5 million cases, there are significant amount of people in each year suffering from angina. Therefore, curing angina pectoris is of high importance (Plomondon, Magid et al. 2007). Although one of the main goals in angina treatment is relief of symptoms, amelioration of the position, especially pain, will unexpectedly cause the ischemia to proceed and so, the consequence will be cardiac injury. Considering this problem, due to American and European drug regulators the anti-anginal medicines also needs to possess anti-ischemia effects, as well. Other purposes of angina pectoris treatment are slowing progression of the disease and reduction of future events, especially heart attacks and, of course, death by treating the underlying heart condition. Treatments for angina include lifestyle changes, medicines, medical procedures, cardiac rehabilitation, and other therapies and will depend on the severity of the symptoms, severity of the underlying disease, and extent of damage to the heart muscle, if any (Parker and Parker 2002; Fernandez, Tandar et al. 2010)." @default.
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• W1573886305 date "2011-10-10" @default.
• W1573886305 modified "2023-09-30" @default.
• W1573886305 title "Conventional and Novel Pharmacotherapy of Angina Pectoris" @default.
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• W1573886305 doi "https://doi.org/10.5772/22767" @default.
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