Matches in SemOpenAlex for { <https://semopenalex.org/work/W1574018602> ?p ?o ?g. }
- W1574018602 endingPage "1841" @default.
- W1574018602 startingPage "1832" @default.
- W1574018602 abstract "Summary Polycyclic aromatic hydrocarbons are among the most hazardous environmental pollutants. However, in contrast to aerobic degradation, the respective degradation pathways in anaerobes are greatly unknown which has so far prohibited many environmental investigations. In this work, we studied the enzymatic dearomatization reactions involved in the degradation of the PAH model compounds naphthalene and 2‐methylnaphthalene in the sulfate‐reducing enrichment culture N 47. Cell extracts of N 47 grown on naphthalene catalysed the sodium dithionite‐dependent four‐electron reduction of the key intermediate 2‐naphthoyl‐coenzyme A ( NCoA ) to 5,6,7,8‐tetrahydro‐2‐naphthoyl‐ CoA ( THNCoA ). The NCoA reductase activity was independent of ATP and was, surprisingly, not sensitive to oxygen. In cell extracts in the presence of various electron donors the product THNCoA was further reduced by a two‐electron reaction to most likely a conjugated hexahydro‐2‐naphthoyl‐ CoA isomer ( HHNCoA ). The reaction assigned to THNCoA reductase strictly depended on ATP and was oxygen‐sensitive with a half‐life time between 30 s and 1 min when exposed to air. The rate was highest with NADH as electron donor. The results indicate that two novel and completely different dearomatizing ring reductases are involved in anaerobic naphthalene degradation. While the THNCoA reducing activity shows some properties of ATP ‐dependent class I benzoyl‐ CoA reductases, NCoA reduction appears to be catalysed by a previously unknown class of dearomatizing aryl‐carboxyl‐ CoA reductases." @default.
- W1574018602 created "2016-06-24" @default.
- W1574018602 creator A5003813316 @default.
- W1574018602 creator A5018083687 @default.
- W1574018602 creator A5033263009 @default.
- W1574018602 creator A5034809012 @default.
- W1574018602 creator A5038842840 @default.
- W1574018602 creator A5040193658 @default.
- W1574018602 creator A5077445480 @default.
- W1574018602 date "2013-01-22" @default.
- W1574018602 modified "2023-10-17" @default.
- W1574018602 title "ATP-dependent/-independent enzymatic ring reductions involved in the anaerobic catabolism of naphthalene" @default.
- W1574018602 cites W1483135821 @default.
- W1574018602 cites W1533773551 @default.
- W1574018602 cites W1546771800 @default.
- W1574018602 cites W1929640200 @default.
- W1574018602 cites W1967450697 @default.
- W1574018602 cites W1967713838 @default.
- W1574018602 cites W1969849442 @default.
- W1574018602 cites W1972827542 @default.
- W1574018602 cites W2016393449 @default.
- W1574018602 cites W2016558929 @default.
- W1574018602 cites W2017583902 @default.
- W1574018602 cites W2022569965 @default.
- W1574018602 cites W2030577520 @default.
- W1574018602 cites W2037668635 @default.
- W1574018602 cites W2041373476 @default.
- W1574018602 cites W2047539645 @default.
- W1574018602 cites W2048687101 @default.
- W1574018602 cites W2059959880 @default.
- W1574018602 cites W2063800001 @default.
- W1574018602 cites W2073647035 @default.
- W1574018602 cites W2075684948 @default.
- W1574018602 cites W2078102242 @default.
- W1574018602 cites W2082511599 @default.
- W1574018602 cites W2085345388 @default.
- W1574018602 cites W2089359137 @default.
- W1574018602 cites W2103343838 @default.
- W1574018602 cites W2121471432 @default.
- W1574018602 cites W2133270719 @default.
- W1574018602 cites W2139602211 @default.
- W1574018602 cites W2149836467 @default.
- W1574018602 cites W2158262346 @default.
- W1574018602 cites W2160149383 @default.
- W1574018602 cites W2320146532 @default.
- W1574018602 cites W2909775845 @default.
- W1574018602 cites W3022314104 @default.
- W1574018602 doi "https://doi.org/10.1111/1462-2920.12076" @default.
- W1574018602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23336264" @default.
- W1574018602 hasPublicationYear "2013" @default.
- W1574018602 type Work @default.
- W1574018602 sameAs 1574018602 @default.
- W1574018602 citedByCount "36" @default.
- W1574018602 countsByYear W15740186022013 @default.
- W1574018602 countsByYear W15740186022014 @default.
- W1574018602 countsByYear W15740186022015 @default.
- W1574018602 countsByYear W15740186022016 @default.
- W1574018602 countsByYear W15740186022017 @default.
- W1574018602 countsByYear W15740186022018 @default.
- W1574018602 countsByYear W15740186022019 @default.
- W1574018602 countsByYear W15740186022020 @default.
- W1574018602 countsByYear W15740186022021 @default.
- W1574018602 countsByYear W15740186022023 @default.
- W1574018602 crossrefType "journal-article" @default.
- W1574018602 hasAuthorship W1574018602A5003813316 @default.
- W1574018602 hasAuthorship W1574018602A5018083687 @default.
- W1574018602 hasAuthorship W1574018602A5033263009 @default.
- W1574018602 hasAuthorship W1574018602A5034809012 @default.
- W1574018602 hasAuthorship W1574018602A5038842840 @default.
- W1574018602 hasAuthorship W1574018602A5040193658 @default.
- W1574018602 hasAuthorship W1574018602A5077445480 @default.
- W1574018602 hasConcept C134651460 @default.
- W1574018602 hasConcept C165474305 @default.
- W1574018602 hasConcept C178790620 @default.
- W1574018602 hasConcept C181199279 @default.
- W1574018602 hasConcept C185592680 @default.
- W1574018602 hasConcept C2779255514 @default.
- W1574018602 hasConcept C2779500173 @default.
- W1574018602 hasConcept C55493867 @default.
- W1574018602 hasConcept C86803240 @default.
- W1574018602 hasConcept C96942376 @default.
- W1574018602 hasConceptScore W1574018602C134651460 @default.
- W1574018602 hasConceptScore W1574018602C165474305 @default.
- W1574018602 hasConceptScore W1574018602C178790620 @default.
- W1574018602 hasConceptScore W1574018602C181199279 @default.
- W1574018602 hasConceptScore W1574018602C185592680 @default.
- W1574018602 hasConceptScore W1574018602C2779255514 @default.
- W1574018602 hasConceptScore W1574018602C2779500173 @default.
- W1574018602 hasConceptScore W1574018602C55493867 @default.
- W1574018602 hasConceptScore W1574018602C86803240 @default.
- W1574018602 hasConceptScore W1574018602C96942376 @default.
- W1574018602 hasIssue "6" @default.
- W1574018602 hasLocation W15740186021 @default.
- W1574018602 hasLocation W15740186022 @default.
- W1574018602 hasOpenAccess W1574018602 @default.
- W1574018602 hasPrimaryLocation W15740186021 @default.
- W1574018602 hasRelatedWork W1969839869 @default.
- W1574018602 hasRelatedWork W1998785179 @default.