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- W1574282316 abstract "The similarity of sex pili mediated by F factors and R(fi + ) factors and the ability of R(fi + ) factors to control by repression the functioning of pilus genes encoded by the F factor suggested that F factors and R(fi + ) factors are closely related. Further comparisons of the episomal properties of F factors and R(fi + ) factors, however, indicated many differences. F factors contain information for a restriction system for phages φII and T7. Cells containing R factors are sensitive to these phages. Furthermore, R(fi + ) factors do not repress the F factor φII restriction system in cells containing both an R(fi + ) factor and an F factor. R factors and F factors are heteroimmune episomes. In addition, an R(fi + ) factor in cells containing both an R factor and an F factor does not fully repress the expression of F-factor immunity to an incoming second F factor. R-factor and F-factor replication systems are not identical. Wild-type F-factor replication genes will complement the mutant F ts114 lac + replication genes in cells containing two F factors. The F ts114 lac + episome is retained when these cells are grown at 42 C; however, cells containing an R(fi + ) factor and F ts114 lac + lose the F ts114 lac + when grown at 42 C, at the same rate as cells containing only the F ts114 lac + . The replication system of the R(fi + ) factor will not complement the mutant F ts114 lac + replication system." @default.
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- W1574282316 date "1970-07-01" @default.
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- W1574282316 title "Comparisons of F Factors and R Factors: Existence of Independent Regulation Groups in F Factors" @default.
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- W1574282316 doi "https://doi.org/10.1128/jb.103.1.81-88.1970" @default.
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