Matches in SemOpenAlex for { <https://semopenalex.org/work/W1574378255> ?p ?o ?g. }
- W1574378255 endingPage "241" @default.
- W1574378255 startingPage "235" @default.
- W1574378255 abstract "Mitochondrial cytochrome c contains a heme group covalently attached through thioether linkages to two cysteinyl residues of the protein. We demonstrate here that the nuclear gene, CYC3, in the yeast Saccharomyces cerevisiae, encodes cytochrome c heme lyase (CCHL), the enzyme catalyzing the attachment of heme to apocytochrome c. Mitochondrial extracts from cyc3- mutants are deficient in CCHL activity compared with extracts from normal strains, whereas strains carrying multiple copies of the CYC3 gene exhibit high levels of the activity. The CYC3 gene was cloned by functional complementation of a cyc3- mutant using a previously isolated plasmid containing the gene PYK1, which is tightly linked to CYC3. An open reading frame encoding a protein of 269 amino acids was identified from the DNA sequence of a fragment encompassing the CYC3 gene, and the corresponding transcript shown to be approximately 0.9 kb in length. CCHL appears to be a single polypeptide chain which acts specifically on the two forms of cytochrome c, but not on cytochrome c1." @default.
- W1574378255 created "2016-06-24" @default.
- W1574378255 creator A5006732358 @default.
- W1574378255 creator A5020229937 @default.
- W1574378255 creator A5073465673 @default.
- W1574378255 creator A5078623413 @default.
- W1574378255 date "1987-01-01" @default.
- W1574378255 modified "2023-10-15" @default.
- W1574378255 title "Identification and sequence of the gene encoding cytochrome c heme lyase in the yeast Saccharomyces cerevisiae." @default.
- W1574378255 cites W1484384142 @default.
- W1574378255 cites W1500388173 @default.
- W1574378255 cites W1519776955 @default.
- W1574378255 cites W1529321087 @default.
- W1574378255 cites W1533548747 @default.
- W1574378255 cites W1552252651 @default.
- W1574378255 cites W1553938468 @default.
- W1574378255 cites W1563062605 @default.
- W1574378255 cites W1590583683 @default.
- W1574378255 cites W1593487575 @default.
- W1574378255 cites W1601687245 @default.
- W1574378255 cites W1603411458 @default.
- W1574378255 cites W1662971183 @default.
- W1574378255 cites W1866329086 @default.
- W1574378255 cites W1881165124 @default.
- W1574378255 cites W1917388543 @default.
- W1574378255 cites W1978641601 @default.
- W1574378255 cites W1998916083 @default.
- W1574378255 cites W2003676968 @default.
- W1574378255 cites W2006370393 @default.
- W1574378255 cites W2006587882 @default.
- W1574378255 cites W2006836034 @default.
- W1574378255 cites W2013456957 @default.
- W1574378255 cites W2019883278 @default.
- W1574378255 cites W2020828649 @default.
- W1574378255 cites W2021289001 @default.
- W1574378255 cites W2026642300 @default.
- W1574378255 cites W2028622989 @default.
- W1574378255 cites W2028888393 @default.
- W1574378255 cites W2036823377 @default.
- W1574378255 cites W2047049388 @default.
- W1574378255 cites W2050611086 @default.
- W1574378255 cites W2056391548 @default.
- W1574378255 cites W2066044857 @default.
- W1574378255 cites W2066586050 @default.
- W1574378255 cites W2078800167 @default.
- W1574378255 cites W2080139629 @default.
- W1574378255 cites W2083579454 @default.
- W1574378255 cites W2098034645 @default.
- W1574378255 cites W2101278035 @default.
- W1574378255 cites W2102131116 @default.
- W1574378255 cites W2103262543 @default.
- W1574378255 cites W2144105488 @default.
- W1574378255 cites W2409180679 @default.
- W1574378255 doi "https://doi.org/10.1002/j.1460-2075.1987.tb04744.x" @default.
- W1574378255 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/553382" @default.
- W1574378255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3034577" @default.
- W1574378255 hasPublicationYear "1987" @default.
- W1574378255 type Work @default.
- W1574378255 sameAs 1574378255 @default.
- W1574378255 citedByCount "221" @default.
- W1574378255 countsByYear W15743782552012 @default.
- W1574378255 countsByYear W15743782552013 @default.
- W1574378255 countsByYear W15743782552014 @default.
- W1574378255 countsByYear W15743782552015 @default.
- W1574378255 countsByYear W15743782552016 @default.
- W1574378255 countsByYear W15743782552017 @default.
- W1574378255 countsByYear W15743782552018 @default.
- W1574378255 countsByYear W15743782552019 @default.
- W1574378255 countsByYear W15743782552020 @default.
- W1574378255 countsByYear W15743782552021 @default.
- W1574378255 countsByYear W15743782552022 @default.
- W1574378255 crossrefType "journal-article" @default.
- W1574378255 hasAuthorship W1574378255A5006732358 @default.
- W1574378255 hasAuthorship W1574378255A5020229937 @default.
- W1574378255 hasAuthorship W1574378255A5073465673 @default.
- W1574378255 hasAuthorship W1574378255A5078623413 @default.
- W1574378255 hasBestOaLocation W15743782551 @default.
- W1574378255 hasConcept C104317684 @default.
- W1574378255 hasConcept C143065580 @default.
- W1574378255 hasConcept C148292235 @default.
- W1574378255 hasConcept C153911025 @default.
- W1574378255 hasConcept C167625842 @default.
- W1574378255 hasConcept C181199279 @default.
- W1574378255 hasConcept C188082640 @default.
- W1574378255 hasConcept C24586158 @default.
- W1574378255 hasConcept C2776217839 @default.
- W1574378255 hasConcept C2777576037 @default.
- W1574378255 hasConcept C2780768313 @default.
- W1574378255 hasConcept C28859421 @default.
- W1574378255 hasConcept C29311851 @default.
- W1574378255 hasConcept C47289529 @default.
- W1574378255 hasConcept C55493867 @default.
- W1574378255 hasConcept C86803240 @default.
- W1574378255 hasConceptScore W1574378255C104317684 @default.
- W1574378255 hasConceptScore W1574378255C143065580 @default.
- W1574378255 hasConceptScore W1574378255C148292235 @default.
- W1574378255 hasConceptScore W1574378255C153911025 @default.
- W1574378255 hasConceptScore W1574378255C167625842 @default.