FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1574694005> ?p ?o ?g. }

• W1574694005 endingPage "9" @default.
• W1574694005 startingPage "1" @default.
• W1574694005 abstract "Background: Hyperphosphatemia remains a common problem in patients receiving maintenance dialysis. Niacinamide inhibits intestinal sodium/phosphorus co transporters and reduces serum phosphorus level in some clinical studies. Objective: Assessment the safety and the efficacy of nicotinamide as adjunctive therapy to calcium carbonate (as phosphate binder). Study design and setting: A prospective, interventional, open-labeled, case control randomized trial was performed at Ain Shams University Specialized Hospital and Al Motamayz hemodialysis center, Cairo, Egypt, from August 2010 to December 2010. Patients and Methods: Sixty hemodialysis patients with serum phosphorus level ≥ 5.0 mg/dl were classified into two groups; group I (control group) in which patients received calcium carbonate tablets in dose of 500mg to 1000mg three t.i.d. And group II (study group) in which patients received calcium carbonate in dose of 500mg to 1000mg t.i.d. and nicotinamide tablets in a dose titrated to 1000mg/day for 8 weeks. Serum calcium, phosphorus and intact parathyroid hormone were measured at week 1 and 9 to assess the efficacy of treatment. Results: Fifty six patients successfully completed the trail. Serum phosphorus level falls significantly from 6.75 to 5.47 mg/dl with group II and not with group I (from 6.46 to 6.53 mg/dl). A concurrent fall in calciumphosphorus product was seen with nicotinamide treatment (from 58.7 to 48.55 mg2/dl2), whereas serum calcium, intact parathyroid hormone, uric acid, platelet count, total cholesterol, hemoglobin, AST, and ALT remained stable in both arms. A trend toward increasing HDL and reducing LDL and triglycerides were reported in nicotinamide group however the overall changes were statistically non significant. Diarrhea and other gastrointestinal disturbances symptoms were the major adverse effects seen with nicotinamide treatment. Conclusion: Nicotinamide in single dose of 1000 mg daily can effectively reduce serum phosphorus level when administered with calcium carbonate (as phosphate binder) with less potential side effects. Key words : Hyperphosphatemia; Hemodialysis; Nicotinamide; Phosphate binder" @default.
• W1574694005 created "2016-06-24" @default.
• W1574694005 creator A5001550993 @default.
• W1574694005 creator A5045792567 @default.
• W1574694005 creator A5048712083 @default.
• W1574694005 date "2012-03-26" @default.
• W1574694005 modified "2023-09-26" @default.
• W1574694005 title "The Effect of Coadminstration of Nicotinamide and Calcium-based Phosphate Binder on Hyperphophatemia in Patients Undergoing Hemodialysis" @default.
• W1574694005 cites W1497510370 @default.
• W1574694005 cites W1965017917 @default.
• W1574694005 cites W1966016104 @default.
• W1574694005 cites W1972478620 @default.
• W1574694005 cites W1974078864 @default.
• W1574694005 cites W1993099421 @default.
• W1574694005 cites W1996819821 @default.
• W1574694005 cites W2001746382 @default.
• W1574694005 cites W2018901137 @default.
• W1574694005 cites W2023485423 @default.
• W1574694005 cites W2030174339 @default.
• W1574694005 cites W2035221187 @default.
• W1574694005 cites W2091399276 @default.
• W1574694005 cites W2102964231 @default.
• W1574694005 cites W2106412070 @default.
• W1574694005 cites W2107207648 @default.
• W1574694005 cites W2127560186 @default.
• W1574694005 cites W2127866713 @default.
• W1574694005 cites W2132700529 @default.
• W1574694005 cites W2135786480 @default.
• W1574694005 cites W2148331513 @default.
• W1574694005 cites W2159293127 @default.
• W1574694005 cites W2168524187 @default.
• W1574694005 cites W2548549197 @default.
• W1574694005 cites W3144430126 @default.
• W1574694005 doi "https://doi.org/10.3968/j.ans.1715787020120501.1001" @default.
• W1574694005 hasPublicationYear "2012" @default.
• W1574694005 type Work @default.
• W1574694005 sameAs 1574694005 @default.
• W1574694005 citedByCount "1" @default.
• W1574694005 countsByYear W15746940052018 @default.
• W1574694005 crossrefType "journal-article" @default.
• W1574694005 hasAuthorship W1574694005A5001550993 @default.
• W1574694005 hasAuthorship W1574694005A5045792567 @default.
• W1574694005 hasAuthorship W1574694005A5048712083 @default.
• W1574694005 hasConcept C126322002 @default.
• W1574694005 hasConcept C134018914 @default.
• W1574694005 hasConcept C178790620 @default.
• W1574694005 hasConcept C181199279 @default.
• W1574694005 hasConcept C185592680 @default.
• W1574694005 hasConcept C2776036575 @default.
• W1574694005 hasConcept C2778063415 @default.
• W1574694005 hasConcept C2779728014 @default.
• W1574694005 hasConcept C2779978075 @default.
• W1574694005 hasConcept C2781208988 @default.
• W1574694005 hasConcept C510538283 @default.
• W1574694005 hasConcept C519063684 @default.
• W1574694005 hasConcept C55493867 @default.
• W1574694005 hasConcept C71924100 @default.
• W1574694005 hasConcept C90924648 @default.
• W1574694005 hasConcept C98274493 @default.
• W1574694005 hasConceptScore W1574694005C126322002 @default.
• W1574694005 hasConceptScore W1574694005C134018914 @default.
• W1574694005 hasConceptScore W1574694005C178790620 @default.
• W1574694005 hasConceptScore W1574694005C181199279 @default.
• W1574694005 hasConceptScore W1574694005C185592680 @default.
• W1574694005 hasConceptScore W1574694005C2776036575 @default.
• W1574694005 hasConceptScore W1574694005C2778063415 @default.
• W1574694005 hasConceptScore W1574694005C2779728014 @default.
• W1574694005 hasConceptScore W1574694005C2779978075 @default.
• W1574694005 hasConceptScore W1574694005C2781208988 @default.
• W1574694005 hasConceptScore W1574694005C510538283 @default.
• W1574694005 hasConceptScore W1574694005C519063684 @default.
• W1574694005 hasConceptScore W1574694005C55493867 @default.
• W1574694005 hasConceptScore W1574694005C71924100 @default.
• W1574694005 hasConceptScore W1574694005C90924648 @default.
• W1574694005 hasConceptScore W1574694005C98274493 @default.
• W1574694005 hasIssue "1" @default.
• W1574694005 hasLocation W15746940051 @default.
• W1574694005 hasOpenAccess W1574694005 @default.
• W1574694005 hasPrimaryLocation W15746940051 @default.
• W1574694005 hasRelatedWork W1562898233 @default.
• W1574694005 hasRelatedWork W1599709350 @default.
• W1574694005 hasRelatedWork W1927855239 @default.
• W1574694005 hasRelatedWork W1993099421 @default.
• W1574694005 hasRelatedWork W2014514461 @default.
• W1574694005 hasRelatedWork W2024934835 @default.
• W1574694005 hasRelatedWork W2033089817 @default.
• W1574694005 hasRelatedWork W2073731863 @default.
• W1574694005 hasRelatedWork W2094710838 @default.
• W1574694005 hasRelatedWork W2161735516 @default.
• W1574694005 hasRelatedWork W2361250833 @default.
• W1574694005 hasRelatedWork W2373085812 @default.
• W1574694005 hasRelatedWork W2385228382 @default.
• W1574694005 hasRelatedWork W2386443415 @default.
• W1574694005 hasRelatedWork W2386473939 @default.
• W1574694005 hasRelatedWork W2741982287 @default.
• W1574694005 hasRelatedWork W2943336184 @default.
• W1574694005 hasRelatedWork W2955654664 @default.
• W1574694005 hasRelatedWork W3028619317 @default.

• next