Matches in SemOpenAlex for { <https://semopenalex.org/work/W1574708246> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1574708246 endingPage "7049" @default.
- W1574708246 startingPage "7042" @default.
- W1574708246 abstract "The yeast gene ALG1 encodes a mannosyltransferase which participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation by catalyzing the formation of dolichol pyrophosphate (Dol-PP)-GlcNAc2Man from GDP-Man and Dol-PP-Glc-NAc2. The DNA region including the ALG1 gene was sequenced and found to contain an open reading frame of 1347 bases. The predicted ALG1 protein contained 449 amino acids (51.9 kDa) with a hydrophobic region near the amino terminus, suggesting it was an integral membrane protein, and four potential sites for N-glycosylation. Disruption of the ALG1 open reading frame by insertion of the URA3 gene showed that the ALG1 gene was essential for viability. Northern analysis and transcript protection showed that the ALG1 gene was transcribed into two classes of messages which differed by about 100 bases at their 5' end and shared a common 3' end. In actively growing cells the short transcript predominated, but as growth slowed the long transcript was more prevalent. The short transcript was predicted to encode the ALG1 protein while the long transcript was predicted to encode a 74-amino acid protein of unknown function. Disruption of the 74-amino acid reading frame, which ended 42 bases upstream of the potential start codon for the ALG1 protein, showed it was not essential for viability." @default.
- W1574708246 created "2016-06-24" @default.
- W1574708246 creator A5053671542 @default.
- W1574708246 creator A5081370900 @default.
- W1574708246 date "1990-04-01" @default.
- W1574708246 modified "2023-10-16" @default.
- W1574708246 title "The sequence and transcript heterogeneity of the yeast gene ALG1, an essential mannosyltransferase involved in N-glycosylation." @default.
- W1574708246 cites W1484322889 @default.
- W1574708246 cites W1500163587 @default.
- W1574708246 cites W1501577595 @default.
- W1574708246 cites W1537782690 @default.
- W1574708246 cites W1559639924 @default.
- W1574708246 cites W1964449641 @default.
- W1574708246 cites W1975304761 @default.
- W1574708246 cites W1975699819 @default.
- W1574708246 cites W1978641601 @default.
- W1574708246 cites W1996010519 @default.
- W1574708246 cites W2003228141 @default.
- W1574708246 cites W2003676968 @default.
- W1574708246 cites W2005115290 @default.
- W1574708246 cites W2014689788 @default.
- W1574708246 cites W2022636296 @default.
- W1574708246 cites W2025763720 @default.
- W1574708246 cites W2029195137 @default.
- W1574708246 cites W2034384239 @default.
- W1574708246 cites W2034740986 @default.
- W1574708246 cites W2042096080 @default.
- W1574708246 cites W2042752473 @default.
- W1574708246 cites W2048398621 @default.
- W1574708246 cites W2048422948 @default.
- W1574708246 cites W2051103528 @default.
- W1574708246 cites W2065232854 @default.
- W1574708246 cites W2071660645 @default.
- W1574708246 cites W2115073295 @default.
- W1574708246 cites W2127667224 @default.
- W1574708246 cites W2134887033 @default.
- W1574708246 cites W2144112248 @default.
- W1574708246 cites W2152708819 @default.
- W1574708246 cites W262216995 @default.
- W1574708246 cites W4254469900 @default.
- W1574708246 doi "https://doi.org/10.1016/s0021-9258(19)39256-7" @default.
- W1574708246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2182636" @default.
- W1574708246 hasPublicationYear "1990" @default.
- W1574708246 type Work @default.
- W1574708246 sameAs 1574708246 @default.
- W1574708246 citedByCount "66" @default.
- W1574708246 countsByYear W15747082462014 @default.
- W1574708246 countsByYear W15747082462015 @default.
- W1574708246 countsByYear W15747082462016 @default.
- W1574708246 countsByYear W15747082462017 @default.
- W1574708246 countsByYear W15747082462018 @default.
- W1574708246 countsByYear W15747082462019 @default.
- W1574708246 countsByYear W15747082462020 @default.
- W1574708246 countsByYear W15747082462021 @default.
- W1574708246 countsByYear W15747082462023 @default.
- W1574708246 crossrefType "journal-article" @default.
- W1574708246 hasAuthorship W1574708246A5053671542 @default.
- W1574708246 hasAuthorship W1574708246A5081370900 @default.
- W1574708246 hasBestOaLocation W15747082461 @default.
- W1574708246 hasConcept C104317684 @default.
- W1574708246 hasConcept C2777313579 @default.
- W1574708246 hasConcept C2778112365 @default.
- W1574708246 hasConcept C2779222958 @default.
- W1574708246 hasConcept C54355233 @default.
- W1574708246 hasConcept C70721500 @default.
- W1574708246 hasConcept C86803240 @default.
- W1574708246 hasConceptScore W1574708246C104317684 @default.
- W1574708246 hasConceptScore W1574708246C2777313579 @default.
- W1574708246 hasConceptScore W1574708246C2778112365 @default.
- W1574708246 hasConceptScore W1574708246C2779222958 @default.
- W1574708246 hasConceptScore W1574708246C54355233 @default.
- W1574708246 hasConceptScore W1574708246C70721500 @default.
- W1574708246 hasConceptScore W1574708246C86803240 @default.
- W1574708246 hasIssue "12" @default.
- W1574708246 hasLocation W15747082461 @default.
- W1574708246 hasOpenAccess W1574708246 @default.
- W1574708246 hasPrimaryLocation W15747082461 @default.
- W1574708246 hasRelatedWork W1973706463 @default.
- W1574708246 hasRelatedWork W1991523530 @default.
- W1574708246 hasRelatedWork W2002128513 @default.
- W1574708246 hasRelatedWork W2009966535 @default.
- W1574708246 hasRelatedWork W2020824267 @default.
- W1574708246 hasRelatedWork W2031436818 @default.
- W1574708246 hasRelatedWork W2075354549 @default.
- W1574708246 hasRelatedWork W2171277769 @default.
- W1574708246 hasRelatedWork W2917539084 @default.
- W1574708246 hasRelatedWork W2092874662 @default.
- W1574708246 hasVolume "265" @default.
- W1574708246 isParatext "false" @default.
- W1574708246 isRetracted "false" @default.
- W1574708246 magId "1574708246" @default.
- W1574708246 workType "article" @default.