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- W1574808554 abstract "The main purpose of randomisation is to avoid bias by distributing the characteristics of patients that may influence outcome randomly between treatment groups so that any difference in outcome can be explained only by treatment. These characteristics might be demographic ones such age or prognostic factors such as clinical history or disease severity. For example menopausal status may influence outcome of treatment for breast cancer.The most elementary form of randomisation is, in the case of two treatments, equivalent to allocating treatment by tossing a coin. Lists for allocating patients by simple randomisation may be constructed with tables of random numbers or random functions on pocket calculators or statistical software. Treatments may then be allocated to patients in sequence using numbered opaque envelopes containing treatment allocations or remotely by phone.While such simple randomisation will on …" @default.
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- W1574808554 date "1998-11-07" @default.
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- W1574808554 title "Understanding controlled trials: Randomisation methods in controlled trials" @default.
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- W1574808554 doi "https://doi.org/10.1136/bmj.317.7168.1301" @default.
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