Matches in SemOpenAlex for { <https://semopenalex.org/work/W1575185537> ?p ?o ?g. }
- W1575185537 endingPage "2570" @default.
- W1575185537 startingPage "2563" @default.
- W1575185537 abstract "Abstract In 1953, noting a remarkable consistency between the agents causing mutations and those associated with cancer, Carl Nordling, a Finnish-born architect, proposed that cancer results from an accumulation of genetic mutations. It is now generally accepted that inherited mutations and environmental carcinogens can lead to the development of premalignant clones. After further mutations, one cell reaches a critical state which confers a survival or growth advantage over normal cells. Such cells have the ability to initiate a malignant tumour. They share many of the features of normal stem cells, including the capacity for self-renewal and differentiation, and are widely termed cancer stem cells (CSCs). Although CSCs have been well characterized in hematological malignancies, their existence in some other tissues has been questioned. Here, we review recent work in which stem cells and stem cell-like cells have been used to investigate the pathogenesis of cancer and potential anticancer treatment strategies, in the context of both hematological and somatic tissue disease. Stem Cells 2014;32:2563–2570" @default.
- W1575185537 created "2016-06-24" @default.
- W1575185537 creator A5002469499 @default.
- W1575185537 creator A5014790331 @default.
- W1575185537 date "2014-09-15" @default.
- W1575185537 modified "2023-09-24" @default.
- W1575185537 title "Concise Reviews: Cancer Stem Cells: From Concept to Cure" @default.
- W1575185537 cites W1484875081 @default.
- W1575185537 cites W1488181476 @default.
- W1575185537 cites W1506568005 @default.
- W1575185537 cites W1560447611 @default.
- W1575185537 cites W1581943791 @default.
- W1575185537 cites W1603547407 @default.
- W1575185537 cites W1622456909 @default.
- W1575185537 cites W1695417215 @default.
- W1575185537 cites W1916309376 @default.
- W1575185537 cites W1950110484 @default.
- W1575185537 cites W1964323367 @default.
- W1575185537 cites W1972642182 @default.
- W1575185537 cites W1977169442 @default.
- W1575185537 cites W1985097493 @default.
- W1575185537 cites W1985370726 @default.
- W1575185537 cites W1988217552 @default.
- W1575185537 cites W1991182407 @default.
- W1575185537 cites W1992772684 @default.
- W1575185537 cites W1993652835 @default.
- W1575185537 cites W1996053472 @default.
- W1575185537 cites W1996898892 @default.
- W1575185537 cites W1999098193 @default.
- W1575185537 cites W2002270177 @default.
- W1575185537 cites W2002924042 @default.
- W1575185537 cites W2003441429 @default.
- W1575185537 cites W2003452068 @default.
- W1575185537 cites W2006898444 @default.
- W1575185537 cites W2009147075 @default.
- W1575185537 cites W2009872043 @default.
- W1575185537 cites W2011681270 @default.
- W1575185537 cites W2012060637 @default.
- W1575185537 cites W2017622605 @default.
- W1575185537 cites W2021835963 @default.
- W1575185537 cites W2027694152 @default.
- W1575185537 cites W2028663226 @default.
- W1575185537 cites W2031633606 @default.
- W1575185537 cites W2031684426 @default.
- W1575185537 cites W2033351451 @default.
- W1575185537 cites W2035244702 @default.
- W1575185537 cites W2037915443 @default.
- W1575185537 cites W2039725378 @default.
- W1575185537 cites W2039753443 @default.
- W1575185537 cites W2042670803 @default.
- W1575185537 cites W2045582876 @default.
- W1575185537 cites W2051592780 @default.
- W1575185537 cites W2052870347 @default.
- W1575185537 cites W2054990794 @default.
- W1575185537 cites W2055134485 @default.
- W1575185537 cites W2058569154 @default.
- W1575185537 cites W2067415629 @default.
- W1575185537 cites W2067771641 @default.
- W1575185537 cites W2073917039 @default.
- W1575185537 cites W2080960094 @default.
- W1575185537 cites W2082080609 @default.
- W1575185537 cites W2083922677 @default.
- W1575185537 cites W2084699749 @default.
- W1575185537 cites W2087688974 @default.
- W1575185537 cites W2090263169 @default.
- W1575185537 cites W2092695767 @default.
- W1575185537 cites W2100653050 @default.
- W1575185537 cites W2102727846 @default.
- W1575185537 cites W2106365104 @default.
- W1575185537 cites W2111288554 @default.
- W1575185537 cites W2112904365 @default.
- W1575185537 cites W2117849899 @default.
- W1575185537 cites W2126284790 @default.
- W1575185537 cites W2128450583 @default.
- W1575185537 cites W2130251290 @default.
- W1575185537 cites W2132639855 @default.
- W1575185537 cites W2133569487 @default.
- W1575185537 cites W2145962902 @default.
- W1575185537 cites W2147243234 @default.
- W1575185537 cites W2158255028 @default.
- W1575185537 cites W2159512367 @default.
- W1575185537 cites W2162830250 @default.
- W1575185537 cites W2164244124 @default.
- W1575185537 cites W2164814247 @default.
- W1575185537 cites W2165354678 @default.
- W1575185537 doi "https://doi.org/10.1002/stem.1798" @default.
- W1575185537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25078632" @default.
- W1575185537 hasPublicationYear "2014" @default.
- W1575185537 type Work @default.
- W1575185537 sameAs 1575185537 @default.
- W1575185537 citedByCount "35" @default.
- W1575185537 countsByYear W15751855372014 @default.
- W1575185537 countsByYear W15751855372015 @default.
- W1575185537 countsByYear W15751855372016 @default.
- W1575185537 countsByYear W15751855372017 @default.
- W1575185537 countsByYear W15751855372018 @default.
- W1575185537 countsByYear W15751855372019 @default.
- W1575185537 countsByYear W15751855372020 @default.