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- W1575518063 abstract "The improvement in the survival of multiple myeloma patients has been attributed to autol‐ ogous stem cell transplantation (ASCT) after induction with novel agents [1,2]. Nevertheless, ASCT has not been considered to have a curative potential, maintenance treatment seems to be one of the solutions to decrease the high relapse rates after ASCT [3]. Therefore, allogeneic stem cell transplantation (Allo-SCT) is a potentially curative approach; the role of allo-SCT is still an ongoing debate due to high transplant-related mortality and lack of large prospective randomized studies in the newly diagnosed patients. A retrospective case-matched analysis was performed comparing myeloma patients treated with Allo-SCT with an equal number of patients who received ASCT by European Group for Blood and Bone Marrow Transplant (EBMT) [4]. Overall survival (OS) for the whole patient group was significantly better for the ASCT group compared with those for allo-SCT (Median survival: 34 months vs 18 months, p=. 001). Therefore, we should answer the question of which patients with multiple myeloma have to be directed to allo-SCT modality." @default.
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- W1575518063 date "2013-04-10" @default.
- W1575518063 modified "2023-10-01" @default.
- W1575518063 title "Allogeneic Hematopoetic Cell Transplantation in Multiple Myeloma" @default.
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- W1575518063 doi "https://doi.org/10.5772/54762" @default.
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