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- W1575652863 abstract "Biologic therapy targeting EGFR has been developed for advanced Colorectal cancer (CC). However, biologics are expensive, and methods to identify response to therapy limited. Confocal laser endomicroscopy (CLE) allows in vivo functional imaging of the colorectal mucosa by using topically or systemically administered contrast agents. The detection of fluorescent targeted markers in vivo may provide clinically relevant information for predication or monitoring therapy. Furthermore, fluorescent nanoparticles linked to antibodies (FNPA) may be eventually utilized as a vehicle for in situ targeted therapy. The aim of this study is to determine if FNPA could be used to assess EGFR expression in murine models of CC." @default.
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- W1575652863 date "2012-04-01" @default.
- W1575652863 modified "2023-09-25" @default.
- W1575652863 title "Sa1617 In Vivo Assessments of EGFR Expression Using Confocal Laser Endomicroscopy in Experimental Models of Colon Cancer" @default.
- W1575652863 doi "https://doi.org/10.1016/j.gie.2012.04.406" @default.
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