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- W1575823504 abstract "In a two-year study of 547 hypertensive patients receiving diuretics, the addition of guanadrel sulfate or methyldopa reduced elevated blood pressure to a similar degree and provided good control in 70% of the patients. Guanadrel-treated patients experienced less frequent and less severe drowsiness than methyldopa-treated patients. The frequency of morning orthostatic faintness was low and similar in both treatment groups. Guanadrel produced no tissue toxicity. Guanadrel sulfate, a postganglionic sympathetic inhibitor, is nearly free of central nervous system side effects and is recommended over methyldopa for step 2 therapy when diuretics alone fail to control mild or moderate hypertension." @default.
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- W1575823504 date "1982-11-12" @default.
- W1575823504 modified "2023-09-27" @default.
- W1575823504 title "Guanadrel Sulfate Compared with Methyldopa for Mild and Moderate Hypertension" @default.
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- W1575823504 doi "https://doi.org/10.1002/j.1875-9114.1982.tb03215.x" @default.
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