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- W1576642013 abstract "INTRODUCTION: Implantation of a tissueengineered bridging device into a peripheral nerve injury site would be an attractive alternative to the nerve autograft. Aligned Schwann cells within a tethered collagen gel can promote and guide neuron regeneration in vitro and in vivo. Combining this cellular alignment with plastic compression to stabilise collagen gels produces a robust cellular biomaterial with improved mechanical handling properties, and the potential to support neuronal growth. The aims of this study were (i) to investigate Schwann cell survival during compression of collagen gels, and (ii) to assess whether cellular alignment, achieved in tethered rectangular collagen gels, was retained following compression." @default.
- W1576642013 created "2016-06-24" @default.
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- W1576642013 date "2010-07-01" @default.
- W1576642013 modified "2023-09-27" @default.
- W1576642013 title "Schwann cells in collagen gels survive plastic compression and maintain their alignment: development of a cellular biomaterial for peripheral nerve repair" @default.
- W1576642013 hasPublicationYear "2010" @default.
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