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- W15772103 abstract "Rapid prototyping of real products, which are customized to the needs of individual patients, became very successful in the field of biomaterials recently. But meanwhile the production is increasing, demands for the newly developed materials and new approaches became more and more important. In this respect multi-material functionally graded sintering has been introduced into production of materials. Certain combinations of materials with different mechanical properties tend to be promising in the field of bio-implants production as well as the Rapid prototyping methods such as Selective Laser Sintering (SLS) and 3D printing (3DP). In this study a possibility of application of functionally graded metal structures was evaluated. The two materials, CoCr alloy and Ti6Al4V alloy, were joined together by multi-material sintering procedure. Both materials are known to be used in orthopedics because of their excellent biocompatibility. In this case the testing samples were made as graded structures, having CoCr alloy on one end and Ti6Al4V alloy on the other end. Different sintering temperatures were applied. The obtained samples were tested in terms of biocompatibility where the manufacturing conditions, especially the sintering temperature, and surface structure were taken into account. The used cells were Balb/c Mouse Fibroblasts and the viability was assessed by MMT test. Samples were further examined for influence on PBMC (Peripheral Blood Mononuclear Cells) by Flow Cytometry analysis (FACS)." @default.
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- W15772103 date "2009-01-01" @default.
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- W15772103 title "Biocompatibility of Metal Sintered Materials in Dependence on Multi-Material Graded Structure" @default.
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- W15772103 doi "https://doi.org/10.1007/978-3-540-92841-6_295" @default.
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