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- W1577278152 abstract "Abstract Aim: The aim of our study was to analyse cytokine composition of human milk and its relationship to the development of eosinophilic colitis (EC). Methods: Cytokines were measured by ELISA method in breast milk of 20 mothers of infants who developed EC and 20 controls. Results: We found significantly higher concentrations of interferon‐gamma (IFN‐gamma) (Th1 cytokine) in breast milk received by EC infants compared to controls (p = 0.0004). In contrary, IL‐18 (Th1‐inducing cytokine) was significantly higher in breast milk received by healthy infants comparing to EC infants (p = 0.001). Regulatory cytokine transforming growth factor beta1 (TGF‐beta1) showed higher concentrations in breast milk received by healthy infants, although the difference from EC group was not significant (p = 0.072). Conclusion: The results of our study showed that infants with EC were receiving breast milk with a possibly risky cytokine pattern indicating cytokine imbalance, impaired immunoregulation and the early Th1 shift." @default.
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- W1577278152 date "2010-06-14" @default.
- W1577278152 modified "2023-10-17" @default.
- W1577278152 title "Is there any relationship between cytokine spectrum of breast milk and occurence of eosinophilic colitis?" @default.
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- W1577278152 doi "https://doi.org/10.1111/j.1651-2227.2010.01907.x" @default.
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