FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1577762020> ?p ?o ?g. }

• W1577762020 abstract "This report summarizes selected research efforts oriented toward ameliorating the genotoxic potential of direct coal liquefaction materials through modification or optimization of process conditions. The studies described were conducted to evaluate the utility of optimized distillation for coal liquids from the SRC-I process. SRC-I process solvent was distilled into 50/sup 0/F-range boiling point (bp) cuts. Analysis of amino-PAH (APAH) showed that mutagenic APAHs containing 3 or more rings were found primarily in fractions boiling above 750/sup 0/F. Three microbial tester strains were used to screen for genetically active agents in the SRC-I distillate bp cuts. Reverse mutation with the Ames tester strain TA98 demonstrated that mutagens were concentrated in the bp cuts boiling above 700/sup 0/F. For this tester strain most of the genetic activity in these distillates was attributable to chemical fractions enriched in APAH having 3 or more rings. Mutagenicity data obtained with TA98 was in good agreement with sk in carcinogenesis results from the mouse-skin initiation/promotion (in vivo) test system. The strongest response in the forward mutation assay did not occur in the most carcinogenically active fractions. Results of initiation/promotion experiments used to measure the relative potency of bp cuts as initiators of mouse skin carcinogenesis againmore » showed that fractions boiling above 750/sup 0/F. Compounds reaching their highest concentrations in the highest boiling and most carcinogenically active cut included known carcinogens such as benzo(a)pyrene and dimethyl benzanthracene. Thus, all biomedical test results indicate that consideration should be given to conducting distillation so as to minimize, in the distillate product, the concentrations of those biologically active compounds found in cuts boiling above 700/sup 0/C.« less" @default.
• W1577762020 created "2016-06-24" @default.
• W1577762020 creator A5010376048 @default.
• W1577762020 creator A5024062585 @default.
• W1577762020 creator A5050268001 @default.
• W1577762020 date "1982-07-01" @default.
• W1577762020 modified "2023-10-13" @default.
• W1577762020 title "Chemical characterization and genotoxic potential related to boiling point for fractionally distilled SRC-I coal liquids" @default.
• W1577762020 doi "https://doi.org/10.2172/5320105" @default.
• W1577762020 hasPublicationYear "1982" @default.
• W1577762020 type Work @default.
• W1577762020 sameAs 1577762020 @default.
• W1577762020 citedByCount "6" @default.
• W1577762020 crossrefType "report" @default.
• W1577762020 hasAuthorship W1577762020A5010376048 @default.
• W1577762020 hasAuthorship W1577762020A5024062585 @default.
• W1577762020 hasAuthorship W1577762020A5050268001 @default.
• W1577762020 hasBestOaLocation W15777620201 @default.
• W1577762020 hasConcept C107872376 @default.
• W1577762020 hasConcept C157777378 @default.
• W1577762020 hasConcept C171250308 @default.
• W1577762020 hasConcept C178790620 @default.
• W1577762020 hasConcept C185592680 @default.
• W1577762020 hasConcept C188596812 @default.
• W1577762020 hasConcept C192562407 @default.
• W1577762020 hasConcept C2780841128 @default.
• W1577762020 hasConcept C39432304 @default.
• W1577762020 hasConcept C518851703 @default.
• W1577762020 hasConceptScore W1577762020C107872376 @default.
• W1577762020 hasConceptScore W1577762020C157777378 @default.
• W1577762020 hasConceptScore W1577762020C171250308 @default.
• W1577762020 hasConceptScore W1577762020C178790620 @default.
• W1577762020 hasConceptScore W1577762020C185592680 @default.
• W1577762020 hasConceptScore W1577762020C188596812 @default.
• W1577762020 hasConceptScore W1577762020C192562407 @default.
• W1577762020 hasConceptScore W1577762020C2780841128 @default.
• W1577762020 hasConceptScore W1577762020C39432304 @default.
• W1577762020 hasConceptScore W1577762020C518851703 @default.
• W1577762020 hasLocation W15777620201 @default.
• W1577762020 hasLocation W15777620202 @default.
• W1577762020 hasLocation W15777620203 @default.
• W1577762020 hasOpenAccess W1577762020 @default.
• W1577762020 hasPrimaryLocation W15777620201 @default.
• W1577762020 hasRelatedWork W1993830065 @default.
• W1577762020 hasRelatedWork W2019670667 @default.
• W1577762020 hasRelatedWork W2065853652 @default.
• W1577762020 hasRelatedWork W2899084033 @default.
• W1577762020 hasRelatedWork W2949911667 @default.
• W1577762020 hasRelatedWork W2952309663 @default.
• W1577762020 hasRelatedWork W2952541249 @default.
• W1577762020 hasRelatedWork W3037456415 @default.
• W1577762020 hasRelatedWork W2522733310 @default.
• W1577762020 hasRelatedWork W2734756804 @default.
• W1577762020 isParatext "false" @default.
• W1577762020 isRetracted "false" @default.
• W1577762020 magId "1577762020" @default.
• W1577762020 workType "report" @default.