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- W1578099154 abstract "A high rate of nosocomial infections among patients with severe multiple trauma including severe traumatic brain injury and initial APACHE II score of 15 or more leads to increased length of stay (LOS), costs and high mortality. That makes the prevention of severe nosocomial infections one of the major therapeutic interventions in these patients. Because of a high rate of mixed nosocomial infections with high resistance to antibiotics it is necessary to start antimicrobal therapy with extended-spectrum antibiotics. Taking into account pharmacodynamics, pharmacokinetics and microbiological features of carbapenems, they make the best choice for these patients. In the case of MRSA infection it is necessary to use the combination of carbapenem and vancomycin." @default.
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- W1578099154 date "2005-01-01" @default.
- W1578099154 modified "2023-09-24" @default.
- W1578099154 doi "https://doi.org/10.1186/cc3084" @default.
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